Effect of acth, corticosteroids, and sex hormones on the blood clotting system

Сейфулла, Р. Д.; Maiskii, A. I.

doi:10.1007/bf00785634

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1982

2010

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Cited by 2 publications

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“…The effect of glucocor ticosteroids per se on the coagulation system is therefore of great interest. The majority of investigators find that GCS decreases coagulation times and induces hypercoagul ability [2,5,10,15], but others are of anoth er opinion [6,13,14]. We therefore carried out some laboratory coagulation tests be fore, after short, and after more prolonged treatment with GCS.…”

Section: Introductionmentioning

confidence: 99%

Effect of Glucocorticosteroids on Some Coagulation Tests

Jørgensen

Sørensen

Freund³

1982

Acta Haematol

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Abstract.To investigate the influence of glucocorticosteroids on the coagulation system, some coagulation tests were performed before, after 2 days' and after 6 weeks' treatment with Prednisone® in 23 patients with collagen or hematological diseases. The prothrombin and proconvertin (P&P), plasma antithrombin III (AT-III), and factor VIII related antigen increased significantly, while the activated partial thromboplastin time (APTT), fibrinogen and plasminogen decreased significantly upon Prednisone treatment. Investigations on fibrinolysis were inconclusive.

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Section: Introductionmentioning

confidence: 99%

Effect of Glucocorticosteroids on Some Coagulation Tests

Jørgensen

Sørensen

Freund³

1982

Acta Haematol

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“…TEG in the postoperative period would have been helpful to determine if the dog in this case had a preexisting hypercoagulable state which precipitated the AMI. However, the results would have been difficult to interpret due to the trauma 35 and corticosteroid 36 s administration, which are known to precipitate a hypercoagulable state. No diseases that predispose to thrombus formation were identified on bloodwork, radiographs, surgical exploration, or biopsy.…”

Section: Discussionmentioning

confidence: 99%