Effect of acute standing and prolonged upright activity on left ventricular hemodynamics, systolic and diastolic intervals, and QT-QS2 relationship

Boudoulas, Harisios; Barrington, William; Olson, Stephen; Bashore, Thomas M.; Wooley, Charles F.

doi:10.1016/0002-8703(85)90085-7

Cited by 8 publications

(3 citation statements)

References 36 publications

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“…Figure 5c,d shows the change in average PEP and LVET respectively, measured in milliseconds (ms), for different participants as they transitioned from lying supine to sitting upright and then to standing. The increase in PEP and the decrease in LVET is well documented in prior literature [26,47] and is attributed to changes in preload, contractility, and afterload. Statistically significant differences in both PEP (p < 0.05, paired t-test) and LVET (p < 0.005, paired t-test) were observed when the subjects transitioned from supine to both upright and standing.…”

Section: Resultssupporting

confidence: 56%

A Chest‐Conformable, Wireless Electro‐Mechanical E‐Tattoo for Measuring Multiple Cardiac Time Intervals

Bhattacharya

Nikbakht

Alden

et al. 2023

Adv Elect Materials

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Cardiovascular diseases are the leading cause of death globally. Noninvasive, accurate, and continuous cardiovascular monitoring can enable the preemptive detection of heart diseases and timely intervention to prevent serious cardiac complications. However, unobtrusive, ambulatory, and comprehensive cardiac monitoring is still a challenge as conventional electronics are rigid, heavy, or consume too much power for long‐term measurement. This work presents a thin (200 µm), stretchable (20%), lightweight (2.5 g), wireless, and low‐power (<3 mW) cardiac monitoring device that conforms to the human chest like a temporary tattoo sticker, correspondingly known as an e‐tattoo. This chest e‐tattoo features dual‐mode electro‐mechanical sensing—bio‐electric cardiac signals via electrocardiography and mechanical cardiac rhythm via seismocardiography. A unique peripheral synchronization strategy between the two sensors enables the measurement of systolic time intervals like the pre‐ejection period and the left ventricular ejection time with high accuracy (error = −0.44 ± 8.74 ms) while consuming very low power. The e‐tattoo is validated against clinically approved gold‐standard instruments on five human subjects. The good wearability and low power consumption of this e‐tattoo permit 24‐h continuous ambulatory monitoring.

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Section: Resultssupporting

confidence: 56%

A Chest‐Conformable, Wireless Electro‐Mechanical E‐Tattoo for Measuring Multiple Cardiac Time Intervals

Bhattacharya

Nikbakht

Alden

et al. 2023

Adv Elect Materials

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show abstract

“…The paradoxical increase in pre-ejection period when going from sitting to standing has been demonstrated before (Boudoulas et al, 1985;Sherwood & Turner, 1993;Waldstein et al, 1998), and head-up tilting from supine to upright is also known to systematically increase pre-ejection period (Frey & Kenney, 1979;Lewis et al, 1977;Ovadia, Gear, Thoele, & Marcus, 1995). Importantly, the increase in pre-ejection period during head-up tilting is not abolished by beta blockade (Ovadia et al, 1995).…”

Section: Discussionmentioning

confidence: 99%

“…This reduces end‐diastolic left ventricular filling, which, according to the Frank‐Starling principle, in turn, reduces the contractility of the left myocard. Indeed, end‐diastolic and stroke volume are found to be reduced in the upright position (Boudoulas, Barrington, Olson, Bashore, & Wooley, 1985; Chae & Suh, 1993; Frey et al, 1994; Shannon, Maher, Santinga, Royal, & Wei, 1991; Sherwood & Turner, 1993; Shoemaker et al, 2001; Toska & Walloe, 2002; Waldstein, Neumann, & Merrill, 1998). The decrease in stroke volume is compensated by an increase in heart rate that is secondary to vagal withdrawal and increased cardiac sympathetic activity.…”

Section: Discussionmentioning

confidence: 99%

Effects of variation in posture and respiration on RSA and pre‐ejection period

2005

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The extent to which variation in posture and respiration can confound pre-ejection period and respiratory sinus arrhythmia (RSA) as indices of cardiac sympatho-vagal activity was examined. Within-subjects changes in these measures were assessed in 36 subjects during different postures and (paced) respiratory frequencies. Changes from supine to sitting to standing led to reduced RSA values and longer pre-ejection periods, reflecting the known decrease in vagal but not the increase of sympathetic activity. Multilevel path analysis showed that within-subjects changes in sympatho-vagal balance were faithfully reflected by changes in interbeat interval, but imperfectly by changes in RSA and pre-ejection period. It was concluded that pre-ejection period should be stratified for posture and RSA for respiratory frequency to reliably index changes in sympatho-vagal balance when these factors are prone to change (e.g., during 24-h ambulatory recording)

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Impact of Increasing Intraperitoneal Volume on Left Ventricular Function in Continuous Ambulatory Peritoneal Dialysis Patients

Alpert¹,

Franklin²,

Twardowski³

et al. 1990

Ambulatory Peritoneal Dialysis

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Effect of acute standing and prolonged upright activity on left ventricular hemodynamics, systolic and diastolic intervals, and QT-QS2 relationship

Cited by 8 publications

References 36 publications

A Chest‐Conformable, Wireless Electro‐Mechanical E‐Tattoo for Measuring Multiple Cardiac Time Intervals

A Chest‐Conformable, Wireless Electro‐Mechanical E‐Tattoo for Measuring Multiple Cardiac Time Intervals

Effects of variation in posture and respiration on RSA and pre‐ejection period

Impact of Increasing Intraperitoneal Volume on Left Ventricular Function in Continuous Ambulatory Peritoneal Dialysis Patients

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