Effect of black cumin seed oil on growth, innate immunity and resistance against Pseudomonas fluorescens infection in Nile tilapia Oreochromis niloticus

Dey, Bipul Kumar; Hossain, Md. Mer Mosharraf; Alam, Md. Eftakher

doi:10.1007/s10499-020-00539-8

Cited by 10 publications

(4 citation statements)

References 67 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…oil, octanoic acid (1), thymoquinone (2), thymol (3), p-cymene (4), maculosin (5), hygrine (6), ethyl ester (7), 2-monomyristin (8). 6,82,[84][85][86][87][88] 91,92,95,96 Nigellicine (7), 93 Nigellidine (8), 97,98 Strychnine (9), 99 5), magnoflorine (6), nigelloside (7), quercetin sphorotrioside (8), kaempferol-3,7-diglucoside (9), kaempferol 3-O-rutinoside (10), rutin (11) 100 alpha-hederin (α-HN) (12). 109 Drug Design, Development and Therapy 2024: The content of compounds in extracts, oils and pure isolates from N. sativa seeds has been widely known and applied.…”

Section: Saponinsmentioning

confidence: 99%

See 1 more Smart Citation

Phytochemical Analysis and Anti-Biofilm Potential That Cause Dental Caries from Black Cumin Seeds (Nigella sativa Linn.)

Kurnia,

Padilah,

Apriyanti

et al. 2024

DDDT

View full text Add to dashboard Cite

The oral cavity is an excellent place for various microorganisms to grow. Spectrococcus mutans and Spectrococcus sanguinis are Gram-negative bacteria found in the oral cavity as pioneer biofilm formers on the tooth surface that cause caries. Caries treatment has been done with antibiotics and therapeutics, but the resistance level of S. mutans and S. sanguinis bacteria necessitates the exploration of new drug compounds. Black cumin (Nigella sativa Linn.) is known to contain secondary metabolites that have antioxidant, antibacterial, anti-biofilm, anti-inflammatory and antifungal activities. The purpose of this review article is to present data on the potential of Nigella sativa Linn seeds as anti-biofilm. This article will discuss biofilm-forming bacteria, the resistance mechanism of antibiotics, the bioactivity of N. sativa extracts and seed isolates together with the Structure Activity Relationship (SAR) review of N. sativa compound isolates. We collected data from reliable references that will illustrate the potential of N. sativa seeds as anti-biofilm drug.

show abstract

Section: Saponinsmentioning

confidence: 99%

“…oil, octanoic acid (1), thymoquinone (2), thymol (3), p -cymene (4), maculosin (5), hygrine (6), ethyl ester (7), 2-monomyristin (8). 6 , 82 , 84–88 …”

Section: Biofilm Forming Gram-positive and Gram-negative Bacteriamentioning

confidence: 99%

Phytochemical Analysis and Anti-Biofilm Potential That Cause Dental Caries from Black Cumin Seeds (Nigella sativa Linn.)

Kurnia,

Padilah,

Apriyanti

et al. 2024

DDDT

View full text Add to dashboard Cite

show abstract

“…Several studies of N. sativa on aquatic commodities have shown that its administration can increase the immunity of rainbow trout (Oncorhynchus mykiss) (Awad et al, 2013;Bektaş et al, 2019), tilapia (Oreochromis niloticus) (Elkamel and Mosaad, 2012;Dey et al, 2020), carp (Cyprinus carpio) (Khondoker et al, 2016;Yousefi et al, 2021), climbing perch (Anabas testudineus) (Khatun et al, 2015), rohu (Labeo rohita) (Ali et al, 2020) and pacific whiteleg shrimp (Lei and Xiao-En, 2019;Nur et al, 2020). P. niruri can improve the immunity of catfish Clarias gariepinus (Setiaji et al, 2013), carp (Sunitha et al, 2017, tiger shrimp P. monodon (Direkbusarakom et al, 1995;Vibin et al, 2020), and Pacific whiteleg shrimp (Sukenda et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Combination of Nigella sativa and Phyllanthus niruri as An Immunostimulant for The Prevention of White Spot Disease in Litopenaeus vannamei

Lesmanawati

Manalu

Rahminiwati

et al. 2022

JAFH

View full text Add to dashboard Cite

Pacific whiteleg shrimp (Litopenaeus vannamei) is a very important commodity, which accounts for almost 70% of the total world shrimp production. However, this production is still threatened by disease attacks, one of which is caused by white spot disease (WSD). Herbs are widely used as immunostimulants as an effort to prevent diseases. Black cumin (Nigella sativa) and stone breaker (Phyllanthus niruri) have long been known as excellent immunostimulants in human. This study aimed to evaluate the potential of N. sativa and its combination with P. niruri as an immunostimulant in L. vannamei for preventing WSD. Tested shrimp (±3.0 g) were treated by N. sativa (N), P. niruri (P) and the combination of both (1N:1P, 2/3N:1/3P, 3/4N:1/4P, 1/3N:2/3, 3/5N:2/5P, 1/4N: 3/4P, 2/5N:3/5P) through feed for 28 days. They were then infected by white spot syndrome virus (WSSV) and observed for 7 days. The parameters observed included immune response and production performance. N. sativa was able to reduce the mortality of test shrimp infected with WSSV, with an RPS value of 71%. N. sativa can be combined with P. niruri in the right composition (1/2N:1/2P and 2/3N:1/3P), while the other combinations are antagonistic. The administration of the best treatments in this study, relatively did not affect the value of total hemocyte count, phenoloxidase activity, respiratory burst activity, hemolymph clotting time and production performance of tested shrimp.

show abstract

“…In rats, black cumin hexane extract can increase the activity and index of phagocytosis of monocytes (Akrom & Fatimah, 2015). Dey et al (2020) noted an increase in immune parameters such as phagocytic activity and respiratory bursts in tilapia after being given black cumin. Apart from black cumin, the results of this study also proved that the Gracilaria verrucosa diet could significantly increase the percentage of lymphocytes to 72.3%, while the percentage of monocytes increased to 19.1% but not significantly.…”

mentioning

confidence: 99%

Effectiveness of Herbal Diet Nigella sativa and Gracilaria verrucosa Against Non-specific Immunity of Tilapia (Oreochromis niloticus)

et al. 2023

View full text Add to dashboard Cite

The addition of Nigella sativa and Gracilaria verrucosa to feed is used as a supplement to increase non-specific immunity in tilapia. The addition of herbal supplements is safe for consumption, easy to decompose, has no residue on the fish's body, and does not harm the environment. This study aims to find the effectiveness of the addition of the herbs Nigella sativa and Gracilaria verrucosa to increase non-specific immunity in tilapia. The study used an experimental method with a completely randomized design, applying 4 treatments and 1 control to tilapia. The dietary doses of Nigella sativa were T0 (control, without Nigella sativa), T1 (2.5), T2 (5), T3 (7.5), and T4 (10) (g kg-1 feed). While the dietary doses of Gracilaria verrucosa were T0 (control, without G. verrucosa), T1 (0.5), T2 (1), T3 (1.5), and T4 (2) (g kg-1 feed). The results showed that the percentage of hematocrite increased significantly with the Nigella sativa diet, while on the Gracilaria verrucosa diet, the percentage of hematocrit was not significant. Further, the Nigella sativa diet and the Gracilaria verrucosa diet can significantly increase the percentage of lymphocytes, but not significantly to the percentage of monocytes. In fish farming, the Nigella sativa and Gracilaria verrucosa diets have the potential to be used to increase non-specific immunity in tilapia, but it is more effective to use the Nigella sativa diet at a dose of 5 g kg-1 feed.

show abstract

Effect of black cumin seed oil on growth, innate immunity and resistance against Pseudomonas fluorescens infection in Nile tilapia Oreochromis niloticus

Cited by 10 publications

References 67 publications

Phytochemical Analysis and Anti-Biofilm Potential That Cause Dental Caries from Black Cumin Seeds (Nigella sativa Linn.)

Phytochemical Analysis and Anti-Biofilm Potential That Cause Dental Caries from Black Cumin Seeds (Nigella sativa Linn.)

Combination of Nigella sativa and Phyllanthus niruri as An Immunostimulant for The Prevention of White Spot Disease in Litopenaeus vannamei

Effectiveness of Herbal Diet Nigella sativa and Gracilaria verrucosa Against Non-specific Immunity of Tilapia (Oreochromis niloticus)

Contact Info

Product

Resources

About