Effect of camphor/cyclodextrin complexation on the stability of O/W/O multiple emulsions

Yu, Shan-Chen; Bochot, Amélie; Bas, G. Le; Chéron, Monique; Mahuteau, Jacqueline; Grossiord, J. L.; Seiller, M.; Duchêne, Dominique

doi:10.1016/s0378-5173(03)00261-8

Cited by 43 publications

(22 citation statements)

References 14 publications

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“…Deodorization ratio (%) = × 100 (5) where I raw is the odor intensity of intact fish oil, and I de is the odor intensity of the fish oil capsules deodorized by encapsulation.…”

Section: Deodorization Ratiomentioning

confidence: 99%

“…Also, the unpleasant taste and odor of fish oil can cause deterioration in the quality of food products [3]. Cyclodextrin (CD) has been widely used to prepare inclusion complexes to improve stability and solubility, modify the release of drugs and turn liquid substances into stable powders [4][5][6]. Whey protein concentrate (WPC) is a mixture of globular proteins isolated from whey, a liquid material created as a by-product of cheese production [7].…”

Section: Introductionmentioning

confidence: 99%

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Encapsulation of fish oil using cyclodextrin and whey protein concentrate

Kim

et al. 2011

Biotechnol Bioproc E

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The purpose of this study was to prepare fish oil capsules using Cyclodextrin and whey protein concentrate. γ-cyclodextrin was more effective than β-cyclodextrin in enhancing emulsion stability and encapsulation efficiency. Mixing a larger amount of γ-cyclodextrin with a smaller amount of whey protein concentrate caused smaller particles to be produced. The initial γ-cyclodextrin: whey protein concentrate : xanthan gum ratio was 0.8 : 0.2 : 0.5 this ratio showed 40% loanding capacity and 80% efficiency in the encapsulation of fish oil. In addition, the odor intensity of the encapsulated fish oil was decreased to 30% of its original value.

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“…Deodorization ratio (%) = × 100 (5) where I raw is the odor intensity of intact fish oil, and I de is the odor intensity of the fish oil capsules deodorized by encapsulation.…”

Section: Deodorization Ratiomentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Encapsulation of fish oil using cyclodextrin and whey protein concentrate

Kim

et al. 2011

Biotechnol Bioproc E

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“…The extracted molecule is then directly released in the external phase which ruins the extraction process (Yan & Pal, 2001, 2004Mortaheb et al, 2008). If O/W/O multiple emulsions have been less extensively studied, they can also finds potential applications in food, cosmetics and controlled delivery drugs Mishra & Pandit, 1989;Laugel et al, 1998Laugel et al, , 2000Yu et al, 2003). They are found also in application in separation processes of hydrocarbons (Krishna et al, 1987;Garti & Kovacs, 1991).…”

Section: Multiple Emulsionsmentioning

confidence: 99%

Mass Transfers Within Emulsions Studied by Differential Scanning Calorimetry (DSC) - Application to Composition Ripening and Solid Ripening

Clausse¹,

Drelich²,

Fouconnier³

2011

Mass Transfer - Advanced Aspects

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“…In the current era of nanoparticulate delivery systems, CDs are widely employed in formulating nanoparticles (Kanwar et al, 2011;Perret et al, 2013) and liposomes (Ascenso, 2013;Chen et al, 2014) to enhance drug solubility, stability and loading. Further, CDs have been explored as a stabilizer for emulsions and multiple emulsions (Duchêne et al, 2003;Yu et al, 2003;Mathapa & Paunov, 2013). Formation of a partial inclusion complex between CDs and certain lipophilic guest molecules can convert them from normal oligosaccharides to surfactant-like molecules with more diverse properties (Messner et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

Insights on novel particulate self-assembled drug delivery beads based on partial inclusion complexes between triglycerides and cyclodextrins

Aburahma

2014

Drug Delivery

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Most of the newly designed drug molecules are lipophilic in nature and often encounter erratic absorption and low bioavailability after oral administration. Finding ways to enhance the absorption and bioavailability of these lipophilic drugs is one of the major challenges that face pharmaceutical industry nowadays. In view of that, the purpose of this review is to shed some light on a novel particulate self-assembling system named ''beads'' than can act as a safe carrier for delivering lipophilic drugs. The beads are prepared simply by mixing oils with cyclodextrin (CD) aqueous solution in mild conditions. A unique interaction between oil components and CD molecules occurs to form in situ surface-active complexes which are prerequisites for beads formation. This review mainly focuses on the fundamentals of beads preparation through reviewing present, yet scarce, literature. The key methods used for beads characterization are discussed in details. Also, the potential mechanisms by which beads increase the bioavailability of lipophilic drugs are illustrated. Finally, the related research areas that needs to be addressed in future for optimizing this promising delivery system are briefly outlined.

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Effect of camphor/cyclodextrin complexation on the stability of O/W/O multiple emulsions

Cited by 43 publications

References 14 publications

Encapsulation of fish oil using cyclodextrin and whey protein concentrate

Encapsulation of fish oil using cyclodextrin and whey protein concentrate

Mass Transfers Within Emulsions Studied by Differential Scanning Calorimetry (DSC) - Application to Composition Ripening and Solid Ripening

Insights on novel particulate self-assembled drug delivery beads based on partial inclusion complexes between triglycerides and cyclodextrins

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