Effect of chronic coffee consumption on aortic stiffness and wave reflections in hypertensive patients

Cv, Vlachopoulos; Gg, Vyssoulis; Alexopoulos, Nikolaos; Ai, Zervoudaki; Pg, Pietri; Ka, Aznaouridis; Stefanadis, Christodoulos

doi:10.1038/sj.ejcn.1602577

Cited by 30 publications

(18 citation statements)

References 53 publications

(71 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It is strongly associated with future cardiovascular events as well as all‐cause mortality and has been related directly to target organ damage in EH . Although the impact of numerous factors on PWV has been previously investigated in patients with EH, the effects of acute intense exercise on arterial stiffness remains largely understudied.…”

mentioning

confidence: 99%

Exercise‐Induced Pulse Wave Velocity Changes in Untreated Patients With Essential Hypertension: The Effect of an Angiotensin Receptor Antagonist

Gkaliagkousi

Gavriilaki

Nikolaidou

et al. 2014

J of Clinical Hypertension

View full text Add to dashboard Cite

2This study investigates arterial stiffness changes after acute exercise in young patients with untreated, recently diagnosed grade I essential hypertension (UH) compared with normotensive (NT) individuals and the effect of antihypertensive treatment on this phenomenon. Study 1 consisted of 25 UH and 15 NT patients. UH patients who received treatment were included in study 2 and were followed-up after a 3-month treatment period with an angiotensin II receptor blocker. Aortic pulse wave velocity (PWV) was assessed at baseline, at maximal exercise, and at 10, 30, and 60 minutes later. In UH patients, PWV increased significantly at maximal exercise and 10 and 30 minutes of recovery, despite blood pressure fall to baseline levels. No significant PWV changes were observed in NT patients. Post-treatment PWV levels were significantly decreased and similar to those of NT patients. Arterial stiffness is impaired following high-intensity acute exercise even in the early stages of hypertension. Antihypertensive treatment ameliorates these effects. J Clin Hypertens (Greenwich).

show abstract

mentioning

confidence: 99%

Exercise‐Induced Pulse Wave Velocity Changes in Untreated Patients With Essential Hypertension: The Effect of an Angiotensin Receptor Antagonist

Gkaliagkousi

Gavriilaki

Nikolaidou

et al. 2014

J of Clinical Hypertension

View full text Add to dashboard Cite

show abstract

“…Fig. 13.3 Augmentation index, timing of refl ected waves, and pulse wave velocity in different groups of daily coffee consumption (low, <200 ml/day; moderate, 200-450 ml/day; and high, >450 ml/day (Reproduced with permission from Vlachopoulos et al [ 48 ] …”

Section: Coffee and Caffeinementioning

confidence: 96%

“…The ingestion of caffeine results in a sustained impairment of arterial stiffness, which lasts longer in hypertensive subjects (at least 3 h) compared with normotensives. Interestingly, the unfavorable effect of caffeine is more evident in central hemodynamics than in peripheral pressure [ 48 ] (Fig. 13.3 ), and coffee increases arterial stiffness to a lesser degree than its contained caffeine [ 49 ].…”

Section: Coffee and Caffeinementioning

confidence: 99%

Pharmacologic and Environmental Factors: Coffee, Smoking, and Sodium

2015

View full text Add to dashboard Cite

Given the prognostic role of arterial stiffness and central hemodynamics [ 1 -4 ], a large body of research has focused on the recognition of lifestyle interventions that may either worsen arterial function, and thus, they should be prohibited or at least discouraged, or exert favorable effects, and, consequently, they should be encouraged.Active smoking has shown a detrimental effect on arterial stiffness either in the acute or chronic phase, while passive smoking is not less innocent. Quitting smoking is related to an improvement in the arterial elastic properties. The effect of pharmaceutical aids for smoking cessation, such as varenicline, needs further investigation, while electronic cigarette is an issue of concern that should be further evaluated.Among elements of nutrition, dietary foods and beverages, salt increases blood pressure (BP) and, consequently, arterial stiffness. The unfavorable effect of salt on arterial stiffness may be exerted through BP-independent mechanisms as well, while genetic predisposition to salt-induced vascular damage has also been proposed. Salt restriction is accompanied by a decrease in aortic stiffness, but the recommended daily consumption has to be better defi ned since recent data raise skepticism related to an existence of a J-curve between salt intake and cardiovascular events. Regarding coffee, we should stress that the latter and caffeine are not interchangeable terms, and results of studies should be interpreted in the context of the particular beverage/substance investigated. Generally, caffeine increases aortic stiffness, whereas when ingested in coffee, this effect seems to be ameliorated. Nevertheless, chronic coffee consumption increases aortic stiffness. On the other hand, beverages with substantiated benefi cial effects on arterial function are those that are rich in fl avonoids. Indeed, consumption of foods rich in polyphenols, such

show abstract

“…9 Acute and chronic coffee intake is associated with increased arterial stiffness and wave reflections in healthy subjects and in hypertensive ones. 32,33 Moreover, caffeine intake acutely increases blood pressure 34 and postprandial glucose levels in diabetics subjects -probably due to the increase of catecholamine released. 35 However, data from epidemiological studies concerning the association of coffee consumption with cardiovascular disease risk are conflicting.…”

Section: Discussionmentioning

confidence: 99%

Consumption of a boiled Greek type of coffee is associated with improved endothelial function: The Ikaria Study

et al. 2013

View full text Add to dashboard Cite

Objective: The association of coffee consumption with cardiovascular disease remains controversial. Endothelial function is associated with cardiovascular risk. We examined the association between chronic coffee consumption and endothelium function in elderly inhabitants of the island of Ikaria. Methods: The analysis was conducted on 142 elderly subjects (aged 66-91 years) of the Ikaria Study. Endothelial function was evaluated by ultrasound measurement of flow-mediated dilation (FMD). Coffee consumption was evaluated based on a food frequency questionnaire and was categorized as 'low' (< 200 ml/day), 'moderate' (200-450 ml/day), or 'high' (> 450 ml/day). Results: From the subjects included in the study, 87% consumed a boiled Greek type of coffee. Moreover, 40% had a 'low', 48% a 'moderate' and 13% a 'high' daily coffee consumption. There was a linear increase in FMD according to coffee consumption ('low': 4.33 ± 2.51% vs 'moderate': 5.39 ± 3.09% vs 'high': 6.47 ± 2.72%; p = 0.032). Moreover, subjects consuming mainly a boiled Greek type of coffee had a significantly higher FMD compared with those consuming other types of coffee beverages (p = 0.035). Conclusions: Chronic coffee consumption is associated with improved endothelial function in elderly subjects, providing a new connection between nutrition and vascular health.

show abstract

Effect of chronic coffee consumption on aortic stiffness and wave reflections in hypertensive patients

Cited by 30 publications

References 53 publications

Exercise‐Induced Pulse Wave Velocity Changes in Untreated Patients With Essential Hypertension: The Effect of an Angiotensin Receptor Antagonist

Exercise‐Induced Pulse Wave Velocity Changes in Untreated Patients With Essential Hypertension: The Effect of an Angiotensin Receptor Antagonist

Pharmacologic and Environmental Factors: Coffee, Smoking, and Sodium

Consumption of a boiled Greek type of coffee is associated with improved endothelial function: The Ikaria Study

Contact Info

Product

Resources

About