Effect of Cigarette Smoking on Serum Lipid Profile in Male Population of Udaipur

Singh, Dilip K.

doi:10.4172/2161-1009.1000283

Cited by 28 publications

(33 citation statements)

References 19 publications

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“…Accordingly, our findings may refer to a potential absorptive effect of cigarette smoking and/or moderate coffee consumption (MCC) on the negative consequences of excessive consumption of coffee as shown in the combined effect of both factors by the results of two-way ANOVA test. However, hyperlipidemic levels of LDL-C and TC have been correlated with the separate effect of HCC and cigarette smoking in humans 18,27,28 and animal models. [29][30][31][32] Nevertheless, some studies showed that caffeine has significant effects 11,23 or no effect on the lipid profile.…”

Section: Discussionmentioning

confidence: 99%

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<p>Combined Effect Of Coffee Consumption And Cigarette Smoking On Serum Levels Of Vitamin B12, Folic Acid, And Lipid Profile In Young Male: A Cross-Sectional Study</p>

Abu-Taha

Dagash

Mohammad

et al. 2019

IJGM

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Objective: To investigate the associations of coffee consumption and/or smoking on certain clinical outcomes including total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), vitamin B12, and folic acid in a population of young healthy men. Method: This cross-sectional study was conducted in Amman, Jordan, over 4 months. Participants were approached for study participation and asked to fill a questionnaire about their anthropometric information, habitual smoking, and coffee consumption during the last 3 months. Their fasting blood samples were taken to measure TC and LDL-C. Results: Healthy male participants (n=117) in the age range of 18 to 26 years were recruited. Mean serum TC was higher in heavy coffee consumers (C++) group (≥3 cups/day) with or without smoking (M= 179.9±34.59 mg/dL and 195.94±23.69 mg/dL) in comparison with moderate coffee consumers (C+) group (1-2 cups/day) (M= 158.1±24.82 mg/dL and 177.23 ±34.17 mg/dL), and the mean level was higher in subjects who were coffee consumers only than smokers who were coffee consumers. LDL-C levels were higher in participants who were coffee consumers (M= 103.06±34.82mg/dL and 118.06±19.31 mg/dL) than smokers who were coffee consumers (M= 88.6±22.40 mg/dL and 108.26±37.57 mg/dL). No significant difference was noted regarding HDL-C, vitamin B12, and folic acid. Conclusion: Our findings showed that heavy coffee consumption was more associated with hyperlipidemia than cigarette smoking. Accordingly, we conclude that moderate coffee consumption may reduce the risk of cardiovascular diseases or their consequences in male.

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Section: Discussionmentioning

confidence: 99%

“…47 Nicotine stimulates the secretion of catecholamines which enhances lipolysis. 28 Moreover, caffeine acts synergistically in the presence of lipolytic hormones, such as epinephrine. It was previously pointed that the effect of caffeine on adrenoceptors is dose dependent.…”

Section: Discussionmentioning

confidence: 99%

<p>Combined Effect Of Coffee Consumption And Cigarette Smoking On Serum Levels Of Vitamin B12, Folic Acid, And Lipid Profile In Young Male: A Cross-Sectional Study</p>

Abu-Taha

Dagash

Mohammad

et al. 2019

IJGM

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“…6 Smoking leads to decrease in oestrogen levels, which decreases HDL cholesterol concentration. 7 Smoking leads to hyperinsulinaemia, which decreases the activity of lipoprotein lipase 8 leading to increased concentration of LDL, VLDL and TGL in the serum.…”

Section: Effects Of Cigarette Smokingmentioning

confidence: 99%

Evaluate the Effect of Cigarette Smoking in Lipid Profile, Body Mass Index (Bmi), Blood Pressure (Bp), Resting Heart Rate and Rr Interval in Healthy Smokers and Compare It With Non-Smokers

Agarwal¹,

Gupta²,

Rijhwani³

et al. 2017

jemds

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BACKGROUNDCigarette smoking is an important and independent risk factor for atherosclerosis, coronary artery disease, peripheral vascular disorders, cerebrovascular diseases, cancer and for chronic obstructive airway disease (COAD). Several studies worldwide give the evidence that tobacco either chewed or inhaled alters the lipid profile in normal individuals. 1,2 A recent prediction by World Health Organisation suggests that deaths in India may exceed 1.5 million annually by 2020 by tobacco consumption. 3 The purpose of this study is to evaluate the effect of cigarette smoking in Lipid Profile, Body Mass Index (BMI), Blood Pressure (BP), Resting Heart Rate and RR interval in healthy smokers and compare it with non-smokers. MATERIALS AND METHODS50 healthy male subjects of age 20 -45 years and 50 age matched male smokers attending Mahatma Gandhi Medical College and Hospital who had the history of smoking one or more cigarettes per day regularly for at least past one year. After taking an informed consent from the patient, a complete General and Systemic examination will be done following which Body Mass Index (BMI), ECG and blood test for serum lipids will be done. Total cholesterol, LDL (low density lipoproteins), VLDL (very low-density lipoprotein), TG (triglycerides), HDL (high density lipoprotein), ECG (RR interval), HR (heart rate) and BP (blood pressure) were recorded. RESULTSMean age in cases and controls is 34.42 ± 6.68. Statistically, this difference was insignificant (p > 0.05). In our study, the mean value of total cholesterol level in smokers ranges between 136 -201 (mean 170.38 ± 15.17) and in non-smokers range between 140 -182 (161.69 ± 11.18). Statistically, this difference is significant (p value .001). In our study, the mean value of LDL cholesterol level in smokers ranges between 76 -188 (mean 118.44 ± 35.770) and in non-smokers range between 72 -110 (85.18 ± 8.048). Statistically, this difference is highly significant (p value < .001). In our study, the mean value of VLDL cholesterol level in smokers ranges between 21 -33 (mean 24 ± 2.35) and in non-smokers range between 14 -19 (17.5.888 ± 1.03). Statistically, this difference is highly significant (p value < .001). In our study, the mean value of TG in smokers ranges between 120 -226 (mean 149.58 ± 46.141) and in non-smokers range between 110 -136 (125.30 ± 5.737). Statistically, this difference is highly significant (p value < .001). In our study, mean value of HDL in smokers ranges between 27 -47 (mean 39.96 ± 4.673) and in non-smokers range between 31 -52 (42.74 ± 4.526). Statistically, this difference is significant (p value < .05). In our study, mean value of HDL in smokers ranges between 27 -47 (mean 39.96 ± 4.673) and in non-smokers range between 31 -52 (42.74 ± 4.526). Statistically, this difference is significant (p value < .05). In our study, mean value of SBP in smokers ranges between 120 -146 (mean 131.83 ± 7.16) and in non-smokers range between 119 -144 (129.80 ± 5.4059). Statistically, this difference is non-significant ...

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“…High density protein was significant higher in non-smokers compared to smokers. 15 Shenoi AS et al did case control study on 50 smokers taken as cases and 50 non-smokers with age, weight and dietary habits matched individuals were taken as controls. On evaluation of lipid profile, it was found that total cholesterol, triglycerides, LDL were significantly higher among cases compared to controls.…”

Section: Introductionmentioning

confidence: 99%

A Comparative Study of Effects of Smoking on Lipid Profile Among Healthy Smokers and Non-Smokers

Girish¹,

Harish²

2018

jebmh

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BACKGROUND Coronary artery disease forms a major non-communicable disease in both developed and developing countries. In western countries, older age groups are affected whereas in our country India, it is common among younger age group. Many risk factors have been evaluated. Cigarette smoking contributes for major risk factor for coronary artery disease, atherosclerosis and peripheral vascular disorders. Mechanism of causing coronary artery disease is multifactorial, it has major adverse effects on lipid profile and homocysteine levels which are again risk factors for coronary artery disease. Hence, this study was undertaken to compare the effects of smoking cigarettes/beedis on lipid profile among smokers and non-smokers. MATERIALS AND METHODS It was a case-control study carried out on 50 healthy smokers and 50 healthy age and weight matched non-smokers attending the medicine OPD of Basaveshwara Medical College, Chitradurga from January to April 2017. Subjects in both groups were in the age range of 25-35 yrs., with no history of alcohol abuse, diabetes mellitus, hypertension, hepatic impairment, renal disease or history of drug intake which alter the lipid profile. RESULTS The mean serum total cholesterol, serum triglycerides, serum LDL-cholesterol & serum VLDL-cholesterol were significantly higher while antiatherogenic serum HDL cholesterol were significantly lower in smokers when compared with non-smokers and it was statistically significant (p<0.001). CONCLUSION Present study shows a statistically significant relationship between cigarette smoking and increased lipid profile. Thus, chronic smokers are at the significant risk of developing Coronary Heart Disease. So, smokers should be counselled and encouraged to quit smoking and adopt a healthier life style.

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Effect of Cigarette Smoking on Serum Lipid Profile in Male Population of Udaipur

Cited by 28 publications

References 19 publications

<p>Combined Effect Of Coffee Consumption And Cigarette Smoking On Serum Levels Of Vitamin B12, Folic Acid, And Lipid Profile In Young Male: A Cross-Sectional Study</p>

<p>Combined Effect Of Coffee Consumption And Cigarette Smoking On Serum Levels Of Vitamin B12, Folic Acid, And Lipid Profile In Young Male: A Cross-Sectional Study</p>

Evaluate the Effect of Cigarette Smoking in Lipid Profile, Body Mass Index (Bmi), Blood Pressure (Bp), Resting Heart Rate and Rr Interval in Healthy Smokers and Compare It With Non-Smokers

A Comparative Study of Effects of Smoking on Lipid Profile Among Healthy Smokers and Non-Smokers

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