Effect of coupled graphene oxide on the sensitivity of surface plasmon resonance detection

Abstract

We investigated graphene-oxide-(GO-) coupled surface plasmon resonance (SPR) detection sensitivity for sandwiched antigen-antibody interaction between human and antihuman immunoglobulin G molecules. GO was prepared in a Langmuir-Blodgett solution on gold and dielectric surfaces. Theoretical and experimental data suggest that an increased dielectric spacer thickness reduces resonance shifts for GO-coupled SPR detection as dielectric properties of GO appear to prevail. In general, a metal-enhanced structure was shown to provide a larger resonance shift by plasmonic field enhancement. The far-field properties were described in terms of near-field overlap. The peak resonance shift that was obtained with GO-coupled SPR detection was enhanced to 113% of the resonance shift obtained by conventional thin-film-based SPR detection and may further be improved by GO stacking.

Large graphene-induced shift of surface-plasmon resonances of gold films: Effective-medium theory for atomically thin materials

“…We point out that previous treatments of graphene as an isotropic medium is not accurate, and that the Kretschmann configuration is an excellent platform to measure anisotropic optical constant of 2D material and test 2D effective medium theory due to its strong normal near field on the surface. This picture of graphene as an effective medium is applicable to other atomically thin nanomaterials or layered structure such as such as graphene oxide (GO), reduced GO, transition metal dichalcogenides, 2D material-based nanocomposite or metamaterials, and helps to understand their electromagnetic responses and functionalities such as enhanced SPR sensitivity [33,34,[77][78][79][80][81][82][83].…”

A Review of Graphene-Based Surface Plasmon Resonance and Surface-Enhanced Raman Scattering Biosensors: Current Status and Future Prospects

“…In 2014, Ryu et al also investigated the effect of GO on SPR sensitivity through simulations and experiments on structures composed of gold, GO, and SiO2 as a spacer layer between gold and GO. The results obtained show that the SPR biosensor coupled with GO has an SPR angle shift of 13% than the conventional structure [35]. Another method that can be used to improve the performance of the SPR biosensor is long-range surface plasmon resonance (LRSPR).…”

Hybrid Graphene/Gold Plasmonic Fiber‐Optic Biosensor

“…plasmonic sensing platforms have been proposed, such as graphene/gold, [7][8][9][10] graphene oxide/gold, [11][12][13][14][15] graphene-MoS2/gold [16][17][18] and MX2/silicon/gold. [19] However, most of these studies are preliminary theoretical investigations.…”