2024
DOI: 10.3390/jcm13175032
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Effect of Diflunisal in Patients with Transthyretin Cardiomyopathy: A Pilot Study

Andrea Camblor Blasco,
Ana Devesa,
Luis Nieto Roca
et al.

Abstract: Background: ATTR-CM is becoming more prevalent, and disease-modifying therapy has been investigated in recent years with promising results. Diflunisal has shown TTR-stabilizing properties assessed by biomarkers and echocardiography, but there are no trials addressing the evolution of morphological changes with CMR. Methods and Results: AMILCA-DIFLU is an exploratory pilot study prospective, single-center, non-randomized, open-label clinical trial. Patients diagnosed with ATTR-CM underwent clinical, functional,… Show more

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