Effect of dopant loading on the structural features of silver-doped hydroxyapatite obtained by mechanochemical method

Fakharzadeh, Ashkan; Ebrahimi‐Kahrizsangi, Reza; Nasiri–Tabrizi, Bahman; Basirun, Wan Jefrey

doi:10.1016/j.ceramint.2017.06.136

Cited by 55 publications

(16 citation statements)

References 52 publications

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“…The long‐term response of the ionic doping to the nHAp structure and the possible detrimental effects as a result of these reactions should be examined carefully. In some studies, on the effect of doping rates on the structure, structural changes have been found at the rate of high doping (Baradaran et al, ; Fakharzadeh, Ebrahimi‐Kahrizsangi, Nasiri‐Tabrizi, & Jefrey Basirun, ). We do not expect a structural degradation due to the low rates that we have chosen in our study, however, to observe the reactions that may arise from effects such as possible ion/anion changes that may occur on application region.…”

Section: Resultsmentioning

confidence: 99%

Silver release of Ag (I) doped hydroxyapatite: In vitro study

Erdem

Turkoz

2019

Microscopy Res & Technique

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A material is produced by doping of silver (Ag (I)) which has antibacterial property to nano hydroxyapatite (nHAp), to remove the hipersensitivity in the teeth by closing the dentine tubules or dental micro cracks of the teeth and effective against for some bacteria. The doping of Ag (I) can also produces a toxic effect. Ag (I) can be released from the structure as a result of biological, physical and chemical effects and may cause toxicity. Therefore, it is important to determine whether the presence of Ag (I) has a toxic effect. In this study, Ag (I)-doped nHAp was synthesized by precipitation method and tried to determine the release values as a function of time compared to the doping rate by using the ICP-OES. Also, the products we produce in simulated body fluid were kept for retention periods of 4-20 weeks to determine degradation percentages. A cytotoxicity study was performed to observe the toxic effect that may be caused by possible Ag (I) release. According to the analysis, the release values in all products were observed in ppb level. And it is concluded that the materials produced are not degraded. Cell viability values of more than 70% were obtained. It was observed that the release of Ag (I) bound to Ag (I)-doped nHAp hexagonal structure was very low. It was concluded that the products are not degraded and Ag (I)-doped nHAp to a certain ratio is a biocompatible material that can be used in dentistry for treatment. K E Y W O R D S cytotoxicity, degredation, hydroxyapatite, silver release

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Section: Resultsmentioning

confidence: 99%

Silver release of Ag (I) doped hydroxyapatite: In vitro study

Erdem

Turkoz

2019

Microscopy Res & Technique

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“…In this case, a dramatic decrease in the cell volume could be attributed to the substitution of PO 3 -4 with CO 2 -3 groups in the HA lattice owing to the smaller ionic radius of the carbonate (1.78 Å) than of the phosphate (2.38 Å) [34]. To appraise the lattice mismatch, the inplane (ε a ) and out-of-plane (ε c ) strains were measured by contrasting the lattice parameters of the HA coating with the lattice parameters of unstrained HA [35]:…”

Section: Phase Analysismentioning

confidence: 99%

Severe sink-in occurrence in thermally sprayed hydroxyapatite coating

Saber‐Samandari

Baradaran

Alamara

et al. 2018

PAC

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The performance of orthopaedic and dental implants counts on the ability to appraise the mechanical properties of biomaterials. In the present study, nanoindentation was used to characterize the mechanical properties of thermally sprayed hydroxyapatite-coated commercial pure titanium (HA/CP-Ti). From the XRD patterns, the as-sprayed HA coating showed an inhomogeneous mixture of polycrystalline and amorphous phases along with the formation of the decomposed constituents including tricalcium phosphate (α-TCP), tetracalcium phosphate (TTCP) and calcium oxide (CaO). The SEM micrographs of HA coating indicated some incompletely melted particles on the surface of flattened droplets, where the average pore size was around 0.8 µm. After the loadunload indentation experiment, a clear severe sink-in deformation feature was observed around the residual indentation impression of the amorphous part. In contrast, pileup only occurs during loading for the crystalline part of the coating. In addition, the crystalline part of the coating exhibited a Young's modulus and hardness of around 120.46 and 7.91 GPa, respectively, which were almost 8 and 259% higher than that of the bare CP-Ti substrate. This is the first report on the nanoindentation characterization of the inhomogeneous mixture of various phase structures in thermally sprayed HA coatings.

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“…Metal ions might be incorporated in hydroxyl site, phosphate site or calcium sites of HAp in order to improve its properties [6]. Numerous studies were reported that calcium ions can be replaced by various metal ions which could modify the functionality of HAp [7][8][9]. In the present work, HAp and cobalt doped HAp were synthesized by ultrasonication assisted wet chemical synthesisto examine for physiochemical properties.…”

Section: Introductionmentioning

confidence: 99%

Cobalt Ions Doped Bioactive Ceramics for Biosensor Biomedical Applications

Kurinjinathan¹,

Arul²,

Ramya³

2018

IJCRR

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Cobalt ions doped hydroxyapatite (Co-HAp) was synthesized by ultrasonication assisted co-precipitation route. The phase of HAp was confirmed by XRD analysis. The crystallite size of doped sample was reduced (28%). The functional groupsof HAp were confirmed by FTIR and Raman analysis. Cobalt ions doped samples were showed magnetic behavior. In addition, optical properties of the samples were also carried out. Hence, cobalt ions doped samples could be an excellent candidate in biosensor and biomedical fields.

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Effect of dopant loading on the structural features of silver-doped hydroxyapatite obtained by mechanochemical method

Cited by 55 publications

References 52 publications

Silver release of Ag (I) doped hydroxyapatite: In vitro study

Silver release of Ag (I) doped hydroxyapatite: In vitro study

Severe sink-in occurrence in thermally sprayed hydroxyapatite coating

Cobalt Ions Doped Bioactive Ceramics for Biosensor Biomedical Applications

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