Effect of Eccentric Exercise on Insulin Secretion and Action in Humans

King, Douglas S.; Feltmeyer, T. L.; Baldus, P. J.; Sharp, Rick L.; Nespor, Julia

doi:10.1249/00005768-199205001-01004

Cited by 1 publication

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“…Prolonged responses of insulin to resistance exercise seem to be contradictory. The glucose-stimulated insulin response has been observed to be reduced 1±3 days after moderate-intensity resistance exercise (Fluckey et al 1994), and increased when performing more intense eccentric exercise (King et al 1993). The subjects in the present study did not receive well-controlled glucose loads, but four of the ®ve post-exercise blood samples were drawn 1.5±2 h after standardized meals.…”

Section: Discussionmentioning

confidence: 78%

Hormonal responses to high- and moderate-intensity strength exercise

Raastad¹,

Bjøro²,

Hallén³

2000

European Journal of Applied Physiology

170

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The hormonal responses of nine male, strength athletes to strength exercise were examined. The athletes performed one moderate- and one high-intensity strength exercise workout. In the high-intensity workout, the load was 100% of each subject's three-repetition maximum (3-RM) for squats and front squats, and 100% of each subject's six-repetition maximum (6-RM) for leg extensions. In the moderate-intensity workout, the load was 70% of the high-intensity protocol. Rest periods between sets were 4-6 min for both workouts. Blood samples were taken before, 30 min into, and every 15 min for the 1st h after exercise, and then 3, 7, 11, 22 and 33 h after exercise, thus allowing examination of both the acute and prolonged hormonal responses. Blood samples were analyzed for testosterone, luteinizing hormone (LH), follicle stimulating hormone (FSH), cortisol, adrenocorticotrophic hormone (ACTH), growth hormone (GH), insulin-like growth factor (IGF-1), insulin, sex hormone binding globulin, creatine kinase, total protein, glucose and lactate. The acute responses of testosterone and cortisol were greater during the high-intensity protocol as compared to the moderate-intensity protocol. The cortisol response was associated with an increase in ACTH concentration. LH and FSH showed no response to either protocol. Acute GH responses were not different between protocols. There were great inter-individual differences in acute GH responses to both protocols. There were no significant differences between protocols with regard to prolonged responses for any hormone. In both trials, IGF-1 concentrations were significantly lower at 0800 hours the morning after exercise as compared to concentrations found at 0800 hours the morning before exercise. The mechanisms responsible for reducing IGF-1 concentration in these trials are unclear, and it is not known if this reduction observed 22 hours after exercise is of physiological significance.

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Section: Discussionmentioning

confidence: 78%