Effect of electroacupuncture on global cerebral ischemia‑reperfusion injury in rats: A urine proteome analysis
Xiao Zhang,
Yuting Dai,
Fuguo Ma
et al.
Abstract:BackgroundThis study aimed to investigate dynamic urinary proteome changes of electroacupuncture (EP) on cerebral ischemia‑reperfusion (CI/R) injured rats and to explore the therapeutic biological mechanisms of EP.MethodsFirst, changed urinary proteins were found in EP stimulation in healthy rats. Then, we used a CI/R injury rat model induced by Pulsinelli's four‐vessel occlusion (4‐VO) method to explore the function of EP on urinary proteome in CI/R injury. Urine samples were collected for proteome analysis b… Show more
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