Effect of experimental factors on the properties of PEDOT-NaPSS galvanostatically deposited from an aqueous micellar media for invasive electrodes

Starbird, Ricardo; Bauhofer, W.; Meza-Cuevas, Mario A.; Krautschneider, Wolfgang H.

doi:10.1109/bmeicon.2012.6465500

Cited by 12 publications

(7 citation statements)

References 52 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This correlation was also apparent in this work, with highly porous PEDOT/PF 6 exhibiting the greatest value of CSC. Interestingly, it is PEDOT/PSS with a typical CSC of 10-26 mC/cm 2 [45][46][47] that is a formulation often used in various bioelectronic applications [48]. Although a CSC value determined in this study was in the typical range for PEDOT/PSS (18.4 ± 1.3 mC/cm 2 ), still, this material was found as the least capacitive among investigated PEDOT matrices.…”

Section: Electrochemical Characterizationmentioning

confidence: 57%

Dopant-Dependent Electrical and Biological Functionality of PEDOT in Bioelectronics

et al. 2021

View full text Add to dashboard Cite

The aspiration to interact living cells with electronics challenges researchers to develop materials working at the interface of these two distinct environments. A successful interfacing coating should exhibit both biocompatibility and desired functionality of a bio-integrated device. Taking into account biodiversity, the tissue interface should be fine-tuned to the specific requirements of the bioelectronic systems. In this study, we pointed to electrochemical doping of conducting polymers as a strategy enabling the efficient manufacturing of interfacing platforms, in which features could be easily adjusted. Consequently, we fabricated conducting films based on a poly(3,4-ethylenedioxythiophene) (PEDOT) matrix, with properties modulated through doping with selected ions: PSS− (poly(styrene sulfonate)), ClO4− (perchlorate), and PF6− (hexafluorophosphate). Striving to extend the knowledge on the relationships governing the dopant effect on PEDOT films, the samples were characterized in terms of their chemical, morphological, and electrochemical properties. To investigate the impact of the materials on attachment and growth of cells, rat neuroblastoma B35 cells were cultured on their surface and analyzed using scanning electron microscopy and biological assays. Eventually, it was shown that through the choice of a dopant and doping conditions, PEDOT-based materials can be efficiently tuned with diversified physicochemical properties. Therefore, our results proved electrochemical doping of PEDOT as a valuable strategy facilitating the development of promising tissue interfacing materials with characteristics tailored as required.

show abstract

Section: Electrochemical Characterizationmentioning

confidence: 57%

Dopant-Dependent Electrical and Biological Functionality of PEDOT in Bioelectronics

et al. 2021

View full text Add to dashboard Cite

show abstract

“…The electrode coating was electropolymerized from a monomer (3,4-ethylenedioxythiophene, EDOT) dispersion in a three-electrode cell configuration. The EDOT/SDS/MWCNT/AuNP solution was deposited under galvanostatic conditions using an Autolab PGSTAT 101 supplied by Metrohm (AUTOLAB, model: PGSTAT-302, Utrecht, Netherlands) with a fixed charge density of 120 mC/cm 2 according to previous research [42]. The theoretically calculated measurements were confirmed using a 50 mM hexacyanoferrate redox standard solution.…”

Section: Methodsmentioning

confidence: 99%

Electrochemical Characterization of Mancozeb Degradation for Wastewater Treatment Using a Sensor Based on Poly (3,4-ethylenedioxythiophene) (PEDOT) Modified with Carbon Nanotubes and Gold Nanoparticles

et al. 2019

View full text Add to dashboard Cite

Mancozeb is a worldwide fungicide used on a large scale in agriculture. The active component and its main metabolite, ethylene thiourea, has been related to health issues. Robust, fast, and reliable methodologies to quantify its presence in water are of great importance for environmental and health reasons. The electrochemical evaluation of mancozeb using a low-cost electrochemical electrode modified with poly (3,4-ethylene dioxythiophene), multi-walled carbon nanotubes, and gold nanoparticles is a novel strategy to provide an in-situ response for water pollution from agriculture. Additionally, the thermal-, electrochemical-, and photo-degradation of mancozeb and the production of ethylene thiourea under controlled conditions were evaluated in this research. The mancozeb solutions were characterized by electrochemical oxidation and ultraviolet-visible spectrophotometry, and the ethylene thiourea concentration was measured using ultra-high-performance liquid chromatography high-resolution mass spectrometry. The degradation study of mancozeb may provide routes for treatment in wastewater treatment plants. Therefore, a low-cost electrochemical electrode was fabricated to detect mancozeb in water with a robust electrochemical response in the linear range as well as a quick response at a reduced volume. Hence, our novel modified electrode provides a potential technique to be used in environmental monitoring for pesticide detection.

show abstract

“…Drug loading into the conducting polymers films is based on the fact that these kinds of polymers are electrically oxidized during the polymerization processes, generating charge carriers [9,44,45]. The doping agent (e.g., Dx and κC) is incorporated to the oxidized polymer [46] to maintain charge neutrality.…”

Section: Dexamethasone Release Experiments From the Pedot:κc:dx Coatingmentioning

confidence: 99%

“…Moreover, PEDOT is reported as a promising material for the immobilization of enzymes and other biologically active molecules [2,7,8]. The incorporation of charged molecules into the PEDOT backbone is described through an electrostatic mechanism due to the formation of charge carriers and the doping process during the electropolymerization process [9]. The subsequent release of the charged compounds was reported to be dependent on the polymer thickness and charge applied during the electrochemical stimulus [10][11][12][13].…”

Section: Introductionmentioning

confidence: 99%

Polysaccharide κ-Carrageenan as Doping Agent in Conductive Coatings for Electrochemical Controlled Release of Dexamethasone at Therapeutic Doses

et al. 2020

View full text Add to dashboard Cite

Smart conductive materials are developed in regenerative medicine to promote a controlled release profile of charged bioactive agents in the vicinity of implants. The incorporation and the active electrochemical release of the charged compounds into the organic conductive coating is achieved due to its intrinsic electrical properties. The anti-inflammatory drug dexamethasone was added during the polymerization, and its subsequent release at therapeutic doses was reached by electrical stimulation. In this work, a Poly (3,4-ethylenedioxythiophene): κ-carrageenan: dexamethasone film was prepared, and κ-carrageenan was incorporated to keep the electrochemical and physical stability of the electroactive matrix. The presence of κ-carrageenan and dexamethasone in the conductive film was confirmed by µ-Raman spectroscopy and their effect in the topographic was studied using profilometry. The dexamethasone release process was evaluated by cyclic voltammetry and High-Resolution mass spectrometry. In conclusion, κ-carrageenan as a doping agent improves the electrical properties of the conductive layer allowing the release of dexamethasone at therapeutic levels by electrochemical stimulation, providing a stable system to be used in organic bioelectronics systems.

show abstract

Effect of experimental factors on the properties of PEDOT-NaPSS galvanostatically deposited from an aqueous micellar media for invasive electrodes

Cited by 12 publications

References 52 publications

Dopant-Dependent Electrical and Biological Functionality of PEDOT in Bioelectronics

Dopant-Dependent Electrical and Biological Functionality of PEDOT in Bioelectronics

Electrochemical Characterization of Mancozeb Degradation for Wastewater Treatment Using a Sensor Based on Poly (3,4-ethylenedioxythiophene) (PEDOT) Modified with Carbon Nanotubes and Gold Nanoparticles

Polysaccharide κ-Carrageenan as Doping Agent in Conductive Coatings for Electrochemical Controlled Release of Dexamethasone at Therapeutic Doses

Contact Info

Product

Resources

About