Effect of Fasting Subjects’ Posture on ¹³C‐Urea Breath Test for Detection of Helicobacter pylori Infection

Abstract

These results suggest that posture and mouthwash affect delta 13C value at the 5- and 10-minute points. Sampling at 20 (maybe 15 or 30) minutes for fasting patients in a sitting position is considered to be appropriate for detection of H. pylori infection in a standard two-sampling-point 13C-urea breath test.

Comparative evaluation of urine-based and other minimally invasive methods for the diagnosis of Helicobacter pylori infection

“…These differences might affect the sensitivity of each serological kit, as demonstrated by previous studies. 24,26 Although the diagnostic value of the UBT has been previously reported, [28][29][30][31][32] this test is very expensive and time-consuming. Therefore, the UBT should be used for the confirmation of successful eradication therapy, 8,10,44,48 while it seems not to be adequate for mass surveys for H. pylori infection in large numbers of subjects.…”

“…The urea breath test (UBT) was performed as described previously, 32,43,44 with minor modifications, after overnight fasting. 13 C-Urea (100 mg) dissolved in distilled water was administered.…”

Second-line treatment for Helicobacter pylori infection in Japan: proton pump inhibitor-based amoxicillin and metronidazole regimen

“…[8][9][10] For the urea breath test procedure, patients, in the sitting position, drank 30 ml of tap water containing 100 mg of 13 C-urea after a greater than 5-h fast. Mouth washing was done before and immediately after the dosage.…”

Influence of lansoprazole, famotidine, roxatidine and rebamipide administration on the urea breath test for the diagnosis of Helicobacter pylori infection

“…The urea breath test (UBT) is a simple, non‐invasive, reproducible and accurate method for the diagnosis of Helicobacter pylori infection 1–4 . This test is commonly used for the assessment of H. pylori infection, particularly after eradication therapy 5,6 .…”