Abstract:Introduction: Mesenchymal stem cells (MSC) therapy is a new approach to treat RA. Studies evaluating anti-inflammatory effects of MSCs per RA severity are scarce. Our primary objective was to evaluate anti-inflammatory effects, change in cytokine levels and cartilage regeneration of two different MSC preparations delivered through two different routes of administration in three RA stages: mild, moderate and severe.
Methods: Human-derived umbilical cord tissue MSCs (hUCT-MSCs) and human bone marrow-derived MSC… Show more
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