Nutrient management is a crucial factor and needs consideration for better growth and high yield of green pepper. An experiment was conducted in the experimental farm of Nangarhar University Faculty of Agriculture to evaluate the influence of different methods of biofertilizer on growth and yield performances of green pepper during 2017. The experiment was conducted with randomized complete block design in five treatments and four replications. The treatments were (1) control, (2) traditional method (TM), (3) root dipping (RD), (4) soil application (SA), and (5) root dipping and soil application (RDSA). Results showed that plant length, branch number, fruit number, and fruit weight were significantly different among treatments. RDSA increased branch and fruit numbers, as well as fruit length, compared to other treatments. RDSA had a greater yield which was 5.4 ton per hectare, followed by TM, SA, RD, and control which were 5.1, 4.7, 4.3, and 3.8 ton per hectare, respectively. Economic analysis of fertilizer’s expenses revealed that TM, RDSA, SA, and RD used a huge amount of chemical and biofertilizers. However, RDSA enhanced net income followed by TM, SA, and RD. This research will encourage farmers to adopt with biofertilizers and decrease the use of chemical fertilizers for eco-friendly forming.