“…ATPS formed of polymers (namely polymer-polymer, or polymer-salt) are well-known for advantages, such as low interfacial tension, good biocompatibility, fast and high phase separation rates and low cost [8,12]. However, their performance is significantly affected due to the small difference in polarity between the coexisting phases [18]. Currently, the number of systems capable of forming two aqueous phases is increasing and the alternatives include the use of alcohol/salt [19][20][21], acetonitrile/carbohydrates [22,23], polymers(polyvinyl alcohol -PVA)/dextran [24] and other combinations including ionic liquids (ILs) [25,26].…”