Effect of Levamisol and Vitamine E/ Selenium on Bovine Cellular and Humeral Immunity after Bovine Viral Diarrhea Vaccination

Sayed-Ahmed, Mohamed Z.

doi:10.15406/jdvar.2015.02.00025

Cited by 2 publications

(1 citation statement)

References 19 publications

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“…Examining the key characteristics of blood samples after co-administration of levamisole with various sheep vaccines revealed both long- and short-term immune-protective stimulation of levamisole [ 32 , 33 ]. Levamisole is thought to have a favorable effect on both large and small ruminant animals that affects several aspects of the pre and postparturition period and neonatal immunology [ 34 ]. After administering oral levamisole treatment (2 mg/kg) for 28 days in 30 herds of 2-day-old Holstein calves, no significant differences were observed in the key indicators of packed cell volume, white blood cell count, differential leukocyte count, total serum protein, and illness occurrence between the treatment groups and the control group when compared to the effects of injection.…”

Section: Discussionmentioning

confidence: 99%

Novel combination therapy for respiratory diseases of small ruminants: Field studies of over 10 years

Gholami,

Derakhshanfar,

Gholami

2023

J Adv Vet Anim Res

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Objective: This study aimed to evaluate a new drug combination for small ruminant respiratory diseases to find a better treatment protocol for the potential replacement of older methods. Materials and Methods: A total of 6,886 animals received common respiratory disease therapies out of 15,845 animals that had respiratory disorders. The new combination therapy technique treated the remaining animals (8,968). The animals were given an oral suspension of triclabendazole or levamisole at an initial dosage of 0.2 ml/kg body weight (BW). The following day, 0.2 mg/kg of 1% ivermectin was subcutaneously administered. Then, on the third and fifth days of treatment, a subcutaneous injection of 30 mg/kg BW of florfenicol (30%) was administered. The survival and recovery rates for both groups were tracked throughout a 6-month period of observation. Postmortem and histopathological signs were also assessed. Results: In the group of the novel combination therapy, group A, clinical, postmortem, and his¬topathological signs were significantly reduced compared to group B. Clinical signs and mortality in group A were 90% and 93% lower than in group B, respectively. Animals that received the new combination therapy were healed of their disease and stayed immune for 6 months. Conclusion: This novel therapy demonstrated significant efficacy against respiratory diseases in a 10-year field study. The paper proved that the protocol introduced could be a new therapeutic approach.

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Section: Discussionmentioning

confidence: 99%

Novel combination therapy for respiratory diseases of small ruminants: Field studies of over 10 years

Gholami,

Derakhshanfar,

Gholami

2023

J Adv Vet Anim Res

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Levamizol Uygulanmasının Şarbon Hastalığına Karşı Aşılanmış Sığırlarda Bağışıklık Sistemi Üzerine Etkileri

Doğan

2022

Kocatepe Veterinary Journal

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Bu araştırmada şarbon hastalığına karşı aşılanan sığırlarda levamizol uygulamasının bağışıklık sistemi üzerine olan etkisi araştırıldı. Araştırmada toplam 40 adet sağlıklı sığır kullanıldı. Sığırlar dört eşit gruba ayrıldı. Kontrol grubuna üçer gün arayla ve bir dozu da 10. gün olmak üzere plasebo olarak serum fizyolojik dört defa deri altına enjekte edildi. İkinci gruba (aşı grubu) üçer gün arayla üç kez serum fizyolojik sonrası 10. gün şarbon aşısı deri altı, üçüncü gruba (aşı-levamizol) üçer gün arayla üç kez levamizol çözeltisinden 2.5 mg/kg dozda deri altı ve sonrası 10. gün şarbon aşısı deri altı, dördüncü gruba (levamizol) ise üçer gün arayla üç defa levamizol 2.5 mg/kg dozda deri altı ve sonrası 10. günde serum fizyolojik deri altına enjekte edildi. Aşılama sonrası aşı-levamizol grubunda nötrofil, lenfosit, monosit ve serum İgG miktarının sadece aşı uygulanan gruba göre anlamlı düzeyde (p

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Effect of Levamisol and Vitamine E/ Selenium on Bovine Cellular and Humeral Immunity after Bovine Viral Diarrhea Vaccination

Cited by 2 publications

References 19 publications

Novel combination therapy for respiratory diseases of small ruminants: Field studies of over 10 years

Novel combination therapy for respiratory diseases of small ruminants: Field studies of over 10 years

Levamizol Uygulanmasının Şarbon Hastalığına Karşı Aşılanmış Sığırlarda Bağışıklık Sistemi Üzerine Etkileri

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