2016
DOI: 10.22159/ijpps.2016v8i11.14365
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Effect of Methyl-Β-Cyclodextrin Complexation on the Hypoglycemic and Hypolipidemic Effects of Khellin: Experimental Study

Abstract: ABSRACTObjective: The present work tackled the development and evaluation of inclusion complex of khellin (KH) and methyl-β-cyclodextrin (MβCD). In addition, it tested its possible hypoglycemic and hypolipidemic effects. Methods:Inclusion complexes of KH-MβCD in the presence of water-soluble polymer were prepared by freeze drying (FD), co-evaporation (EV) and kneading methods (KN). The selected ternary complex was characterized by Fourier transform infrared spectrophotometry (FTIR), x-ray diffractometry (XRD),… Show more

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