Effect of molecular weight of starch on the properties of cassava starch microspheres prepared in aqueous two-phase system

Xia, Huiping; Li, Bingzheng; Gao, Qunyu

doi:10.1016/j.carbpol.2017.08.074

Cited by 43 publications

(16 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Some ridges were also identified that appear to mark sites where granules were in close contact with one another. These observations were in parallel with morphological studies of native cassava starch conducted by Charoenkul et al [28] and Xia et al [29]. The microscopic analysis of MCPS showed small pores were detected in minimal amount and the starch granule surface appeared to be rough and wave-like creases were spotted as reported by Palacios-Fonseca et al [30].…”

Section: Characterization Of Native and Modified Starchsupporting

confidence: 85%

Synthesis and Characterization of Dual Properties Coagulant from Natural Precursors for Raw Water Treatment

Asharuddin

Othman

Zin

et al. 2020

IJIE

View full text Add to dashboard Cite

A novel coagulant with dual properties was produced by manipulating the chemical characteristics of natural precursors. In the present study, cassava peel starch (CPS) was isolated from agriculture waste and lemongrass extract was procured using soxhlet extraction using ethanol. A preliminary study consisting of chemical analysis and antimicrobial test was done onto the lemongrass extract to ensure the presence of the active group responsible for antimicrobial effect. The modified cassava peel starch (MCPS) was synthesized using novel acidalkali grafting method to incorporate active compounds from lemongrass extract onto the starch backbone. The modified starch was subjected to Scanning Electron Microscopy coupled with Electron Dispersive X-Ray Spectrometry (SEM-EDX) for surface morphological and elementral distribution analysis. The molecular composition analysis was accomplished using Fourier Transform Infrared Spectrophotometry (FTIR) while the efficacy of the modification process was further analyze using proton Nuclear Magnetic Resonance Spectroscopy (1H NMR). The SEM-EDX and FTIR results revealed impressive changes in the physical surface morphology, elemental distribution and chemical structure of the starch post-modification. The results also indicated successful integration of lemongrass active groups onto the starch molecules which provides promising potential of the modified starch towards proposed application for water clarification and disinfection.

show abstract

Section: Characterization Of Native and Modified Starchsupporting

confidence: 85%

Synthesis and Characterization of Dual Properties Coagulant from Natural Precursors for Raw Water Treatment

Asharuddin

Othman

Zin

et al. 2020

IJIE

View full text Add to dashboard Cite

show abstract

“…The physicochemical properties of PLGA MPs are determined by several factors: production method (Busatto et al 2018;Wang et al 2015), processing and sterilization (Keles et al 2015), kind of polymers (i.e., polymer functionalization, molecular weight, and monomer composition) (Beck-Broichsitter et al 2016;Ni et al 2017;Washington et al 2018;Xia et al 2017), drug (Capan et al 2003), formulations parameters (Hernández-Giottonini et al 2020), presence of excipients such as porogen agents (Oh et al 2011), osmotic agents, stabilizers, surfactants (Li et al 2018).…”

Section: Physicochemical Characterization: Morphology Size Aerodynamentioning

confidence: 99%

“…Other methods/analyses have been recently reported in literature to evaluate encapsulation efficacy and structural and chemical integrity of drugs. For example, thermogravimetry analysis (TGA), glass transition (T g ) temperature measured using differential scanning calorimetry (DSC) (Dwivedi et al 2018), attenuated total reflectance-Fourier transform infrared (ATR-FTIR) (Noviendri et al 2016) and X-ray diffraction (XRD) (Xia et al 2017) of PLGA MPs were employed for controlling drug stability. The interaction between drug and polymer can be studied by FITR spectroscopy: Keles et al (2014) used FTIR spectroscopic imaging to evaluate the redistribution and release of hGH from a range of PLGA/PLA MPs.…”

Section: Drug Encapsulation and Its Loading Efficiency Evaluationmentioning

confidence: 99%

“…Here, the focus is on a random copolymer of poly-(glycolic acid) (PGA) and poly-(lactic acid) (PLA) ( Fig. 1), which employment is mostly due to the possibility to achieve a controlled drug release by governing its bio-degradation which is ruled by the polymer chemistry such as glycoside units content, initial MW (Amoyav et al 2019;Xia, Li, and Gao 2017;Hussain et al 2017), stereochemistry (composition in d and l) (Makadia and Siegel 2011) or end-group functionalization (Wang et al 2019).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Recent advances in the formulation of PLGA microparticles for controlled drug delivery

et al. 2020

View full text Add to dashboard Cite

Polymeric microparticles (MPs) are recognized as very popular carriers to increase the bioavailability and bio-distribution of both lipophilic and hydrophilic drugs. Among different kinds of polymers, poly-(lactic-co-glycolic acid) (PLGA) is one of the most accepted materials for this purpose, because of its biodegradability (due to the presence of ester linkages that are degraded by hydrolysis in aqueous environments) and safety (PLGA is a Food and Drug Administration (FDA)-approved compound). Moreover, its biodegradability depends on the number of glycolide units present in the structure, indeed, lower glycol content results in an increased degradation time and conversely a higher monomer unit number results in a decreased time. Due to this feature, it is possible to design and fabricate MPs with a programmable and time-controlled drug release. Many approaches and procedures can be used to prepare MPs. The chosen fabrication methodology influences size, stability, entrapment efficiency, and MPs release kinetics. For example, lipophilic drugs as chemotherapeutic agents (doxorubicin), anti-inflammatory non-steroidal (indomethacin), and nutraceuticals (curcumin) were successfully encapsulated in MPs prepared by single emulsion technique, while water-soluble compounds, such as aptamer, peptides and proteins, involved the use of double emulsion systems to provide a hydrophilic compartment and prevent molecular degradation. The purpose of this review is to provide an overview about the preparation and characterization of drug-loaded PLGA MPs obtained by single, double emulsion and microfluidic techniques, and their current applications in the pharmaceutical industry. Graphic abstract

show abstract

“…It was found that polyethylene glycol (PEG) could precipitate dextrin like ethanol . In addition, crystalline starch microspheres were successfully prepared in an aqueous two‐phase system formed by starch and PEG . These results suggested that the presence of PEG might affect crystallization of short‐chain amylose.…”

Section: Introductionmentioning

confidence: 98%

Crystallization of Short‐Chain Amylose: Effect of the Precipitant

et al. 2019

View full text Add to dashboard Cite

The effects of ethanol and polyethylene glycol (PEG) on crystallization of short‐chain amylose are investigated. In the absence of precipitants, the yield of short‐chain amylose precipitate is 38.8%, while the presence of ethanol and PEG increases the yield to 45.1% and 54.7%, respectively. Moreover, the crystallinity of the precipitate obtained without the precipitants is 45.4%, while the presence of ethanol and PEG increases the crystallinity to 50.4% and 48.6%, respectively. In the absence of precipitants, the precipitate shows B‐type crystallinity and is spherical with the size <1 µm. In the presence of ethanol, the precipitate displays A‐type crystallinity and an elongated platelet shape with the length >1 µm. The precipitate obtained in the presence of PEG is also B‐type and spherical but is smaller than the precipitate obtained in the absence of precipitants. These results suggest that ethanol and PEG significantly affect crystallization of short‐chain amylose in different ways.

show abstract

Effect of molecular weight of starch on the properties of cassava starch microspheres prepared in aqueous two-phase system

Cited by 43 publications

References 42 publications

Synthesis and Characterization of Dual Properties Coagulant from Natural Precursors for Raw Water Treatment

Synthesis and Characterization of Dual Properties Coagulant from Natural Precursors for Raw Water Treatment

Recent advances in the formulation of PLGA microparticles for controlled drug delivery

Crystallization of Short‐Chain Amylose: Effect of the Precipitant

Contact Info

Product

Resources

About