Effect of pH and temperature on the formation of hydroxyapatite at low temperatures by decomposition of a Ca–EDTA complex

Microstructure of hydroxyapatite- and octacalcium phosphate-coatings formed on magnesium by a hydrothermal treatment at various pH values

“…On the other hand, the crystal shape, size and crystallographic orientation of synthesized HAp particles or flakes have been well investigated [23][24][25][26][27][28][29][30]. It was revealed that these factors affect cytokine production [31,32], the proliferation of tumor cells [33] and luminescence properties [25].…”

Shape-controlled synthesis of F-substituted hydroxyapatite microcrystals in the presence of Na2EDTA and citric acid

“…Over the past decades, a number of synthetic routes have been developed to produce HAp and/or FHAp crystals with a variety of shapes and morphologies [17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35]. Owing to its simple synthetic processes and low total costs, hydrothermal technique is a highly efficient route to the preparation of HAp and/or FHAp crystals of high crystallinity with distinct morphological features.…”

Morphology control of hydroxyapatite through hydrothermal process

“…Using chelate to produce hexagonal hydroxyapatite in hydrothermal condition is a simple process and can produce well-crystallized product with a relatively large size. In previous works, EDTA has been used to produce HAP, but none of them have given a possible mechanism of the HAP crystal in the presence of EDTA [9,10].…”