“… 2 Endocrine therapy with a duration of 5 to 10 years is a standard of care for HR-positive disease, which accounts for approximately 70% of all breast cancers. 3 , 4 , 5 Radiotherapy applies to all individuals who underwent breast-conserving surgery and may be used for patients with a tumor larger than 5 cm or with node-positive disease after mastectomy. Chemotherapy is recommended for patients with ERBB2 -positive and HR-negative tumors, node-positive disease, and high Oncotype recurrence scores in HR-positive and ERBB2 -negative breast cancer.…”