Effect of selected aldehydes on the growth and fermentation of ethanologenicEscherichia coli

Zaldivar, Jesus; Martı́nez, Alfredo; Ingram, L. O.

doi:10.1002/(sici)1097-0290(19991005)65:1<24::aid-bit4>3.0.co;2-2

Cited by 400 publications

(134 citation statements)

References 36 publications

Supporting

Mentioning

123

Contrasting

Unclassified

Order By: Relevance

“…The effect can be superior by the presence of xylose and glucose degradation products such as furfural and its derivative caused by acid and heat (Zaldivar et al, 1999). Hence, biologically degradation products of lignin could lessen the harmful effect during enzymatic hydrolysis.…”

Section: Total Phenolic Compounds As Indicator Of Lignin Modificationmentioning

confidence: 99%

Enhancement of fermentable sugars production from oil palm empty fruit bunch by ligninolytic enzymes mediator system

Zanirun

Bahrin

Phang

et al. 2015

International Biodeterioration & Biodegradation

View full text Add to dashboard Cite

Section: Total Phenolic Compounds As Indicator Of Lignin Modificationmentioning

confidence: 99%

Enhancement of fermentable sugars production from oil palm empty fruit bunch by ligninolytic enzymes mediator system

Zanirun

Bahrin

Phang

et al. 2015

International Biodeterioration & Biodegradation

View full text Add to dashboard Cite

“…Other aldehydes known to be present in dilute acid hydrolysates of hemicellulose [21,26] were also tested at various concentrations using LY180(pLOI4900) and LY180 yqhC(pLOI4900). All increased luciferase activity by 2-to 5-fold in LY180(pLOI4900) in comparison with untreated cells (data not shown).…”

Section: Is10mentioning

confidence: 99%

“…Furfural is metabolized to furfuryl alcohol by NADPHdependent oxidoreductases in yeast [9,21,24] and bacteria [2,6,26]. In E. coli, growth is inhibited by the addition of furfural at concentrations below 1.0 g l ¡1 but resumed following conversion of furfural to furfuryl alcohol [17,18].…”

Section: Introductionmentioning

confidence: 99%

YqhC regulates transcription of the adjacent Escherichia coli genes yqhD and dkgA that are involved in furfural tolerance

Turner

Miller

Jarboe

et al. 2010

J Ind Microbiol Biotechnol

Self Cite

View full text Add to dashboard Cite

Previous results have demonstrated that the silencing of adjacent genes encoding NADPH-dependent furfural oxidoreductases (yqhD dkgA) is responsible for increased furfural tolerance in an E. coli strain EMFR9 [Miller et al., Appl Environ Microbiol 75:4315-4323, 2009]. This gene silencing is now reported to result from the spontaneous insertion of an IS10 into the coding region of yqhC, an upstream gene. YqhC shares homology with transcriptional regulators belonging to the AraC/XylS family and was shown to act as a positive regulator of the adjacent operon encoding YqhD and DkgA. Regulation was demonstrated by constructing a chromosomal deletion of yqhC, a firefly luciferase reporter plasmid for yqhC, and by a direct comparison of furfural resistance and NADPH-dependent furfural reductase activity. Closely related bacteria contain yqhC, yqhD, and dkgA orthologs in the same arrangement as in E. coli LY180. Orthologs of yqhC are also present in more distantly related Gram-negative bacteria. Disruption of yqhC offers a useful approach to increase furfural tolerance in bacteria.

show abstract

“…1) are the most potent inhibitory compounds generated from acid pretreatment of lignocelluloses to simple sugars for fermentation (Zaldivar et al, 1999).…”

Section: Article Infomentioning

confidence: 99%

Furfural and 5-HMF: Potent fermentation inhibitors and their removal techniques

Malav¹,

Prasad²,

Sheetal³

et al. 2017

Int.J.Curr.Microbiol.App.Sci

View full text Add to dashboard Cite

Effect of selected aldehydes on the growth and fermentation of ethanologenicEscherichia coli

Cited by 400 publications

References 36 publications

Enhancement of fermentable sugars production from oil palm empty fruit bunch by ligninolytic enzymes mediator system

Enhancement of fermentable sugars production from oil palm empty fruit bunch by ligninolytic enzymes mediator system

YqhC regulates transcription of the adjacent Escherichia coli genes yqhD and dkgA that are involved in furfural tolerance

Furfural and 5-HMF: Potent fermentation inhibitors and their removal techniques

Contact Info

Product

Resources

About