Effect of surface modification on the in vitro calcium phosphate growth on the surface of poly(methyl methacrylate) and bioactivity

Choi, Sunmi; Yang, Won-Kyu; Yoo, Yong-Won; Lee, Woo-Kul

doi:10.1016/j.colsurfb.2009.11.012

Cited by 33 publications

(13 citation statements)

References 32 publications

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“…According to EDS analysis, the average Ca/P ratio of the nHA coating was 1.57, rounded up to 1.6. Although OCP has been shown to be cytocompatible,49 further cell studies are still needed to confirm that.…”

Section: Resultsmentioning

confidence: 99%

The effects of nanostructured hydroxyapatite coating on the biodegradation and cytocompatibility of magnesium implants

Iskandar

Aslani

Liu

2013

J Biomedical Materials Res

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Magnesium (Mg) alloys, a novel class of degradable, metallic biomaterials, have attracted growing interest as a promising alternative for medical implant and device applications due to their advantageous mechanical and biological properties. Although its biodegradability is an attractive property, rapid degradation of Mg in the physiological environments imposes a major obstacle that limits the translation of Mg-based implants to clinical applications. Therefore, the objective of this study was to develop a nanostructured hydroxyapatite (nHA) coating on polished Mg substrates to mediate the rapid degradation of Mg while improving its integration with bone tissue for orthopedic applications. The nHA coatings were deposited on polished Mg using the patented transonic particle acceleration (Spire Biomedical) process. Surface morphology, elemental compositions, and crystal structures were characterized using scanning electron microscopy, energy dispersive X-ray spectroscopy, and X-ray diffraction (XRD) analysis, respectively. The degradation of nHA-coated and non-coated Mg samples was investigated by incubating the samples in phosphate buffered saline and revised simulated body fluid, under standard cell culture conditions. Rat bone marrow stromal cells (BMSCs) were harvested and cultured with nHA-coated and non-coated Mg samples to determine cytocompatibility. The degradation results suggested that the nHA coatings decreased Mg degradation. Improved BMSC adhesion was observed on the surfaces of the nHA-coated and non-coated Mg samples, in comparison with the cells on the culture plate surrounding the Mg samples. In conclusion, nHA coatings showed promise for improving the biodegradation and cytocompatibility properties of Mg-based orthopedic implants and should be further studied.

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Section: Resultsmentioning

confidence: 99%

The effects of nanostructured hydroxyapatite coating on the biodegradation and cytocompatibility of magnesium implants

Iskandar

Aslani

Liu

2013

J Biomedical Materials Res

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“…Calcification may be on the outer surface or in the inner part of the IOL. 19 Calcium content of normal aqueous humour is low and is half of the serum level. Any cause of a localized increase in calcium and phosphorus may result in dystrophic calcification which can be derived from residual cataractous lens material and inadequate cortex cleaning during cataract surgery.…”

Section: Discussionmentioning

confidence: 99%

Total Opacification of Intraocular Lens Implant After Uncomplicated Cataract Surgery: A Case Report

Jarwal¹

2019

DJO

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The introduction a few years ago of hydrophilic acrylic intraocular lenses (IOLs) a few years ago constituted a major advance in the field of Cataract Surgery. These lenses have become increasingly popular, thanks to the ease with which they can be folded and implanted in the capsular sac through a small incision; their good medium and long-term tolerance attributable to the great biocompatibility of the material employed; and the ease with which YAG laser capsulotomy can be performed where required, without damaging the lens and thus minimizing certain complications. Different models have been developed, generally offering good short-and middle-term vision performance, though little is known of their potential long-term results and complications. 1 These complications include opacification of IOLs, which has been recognized for several years. 3 Most reported cases have been late opacification of hydrophilic acrylic IOLs. 4-10 Opacification reduces visual acuity (VA) and it requires some intervention. We report the clinical history and management of a cases of progressive opacification in hydrophilic yellow acrylic IOLs.

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“…Calcification may be on the outer surface or in the inner part of the IOL. 3 Though all types of IOL can undergo opacification, Hydrophilic Acrylic IOLs are commonly known to opacify due to deposition of Calcium phosphate crystals on the optic. 4 Hydrophobic Acrylic IOLs are known to opacify, called glistening due to the formation of small fluid-filled vacuoles within the optic of the IOL.…”

Section: Image 4 Haptic Dialed Into Anterior Chamber and Removal Of mentioning

confidence: 99%

Tips and Tricks for Surgical Management of Opacified IOL

Mahesha¹,

Sastry²,

Suryakanth³

2019

jebmh

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The opacification of hydrophilic acrylic IOLs is a serious complication of unknown etiology, with the only effective treatment being lens explantation and replacement, preferably with a lens of some different material. 1 IOL exchange for opacified lens can be difficult and challenging. Surgery may not always go on according to the pre-operative plan and the surgeon must be ready with an alternative during surgery. We present a series of cases of IOL opacification that posed challenges in diagnosis and the various surgical management techniques.

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Effect of surface modification on the in vitro calcium phosphate growth on the surface of poly(methyl methacrylate) and bioactivity

Cited by 33 publications

References 32 publications

The effects of nanostructured hydroxyapatite coating on the biodegradation and cytocompatibility of magnesium implants

The effects of nanostructured hydroxyapatite coating on the biodegradation and cytocompatibility of magnesium implants

Total Opacification of Intraocular Lens Implant After Uncomplicated Cataract Surgery: A Case Report

Tips and Tricks for Surgical Management of Opacified IOL

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