Effect of three different compositions of topical fluoride varnishes with and without prior oral prophylaxis on Streptococcus mutans count in biofilm samples of children aged 2–8 years: A randomized controlled trial

Yadav, Sushma; Sachdev, Vinod; Malik, Manvi; Chopra, Radhika

doi:10.4103/jisppd.jisppd_62_19

Cited by 12 publications

(7 citation statements)

References 15 publications

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“…A change in either pH or the presence of free radical ions can create a desired anticariogenic environment, as previously noted in the literature [ 48 , 49 ]. Another explanation is the limitation of assessing the effect of GC Tooth Mousse Plus® just by focusing on remineralisation.…”

Section: Discussionmentioning

confidence: 71%

Effectiveness of Visual-Tactile Examination and DIAGNOdent Pen in Detecting Early Enamel Caries and Its Remineralisation: An In Vitro Study

Rashid

Karobari

Halim

et al. 2022

BioMed Research International

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Background. The caries preventive effect of Colgate Duraphat® and GC Tooth Mousse Plus® has been widely studied, but the remineralisation potential of initial occlusal caries using these two remineralisation materials remains unclear. Aim. This study is aimed at evaluating and comparing the remineralisation of early enamel caries on the occlusal surface of permanent posterior teeth using ICDAS II caries scoring system and DIAGNOdent Pen (DDPen) after remineralisation with Colgate Duraphat® and GC Tooth Mousse Plus®. Materials and Methods. Extracted posterior teeth ( N = 120 ) with incipient occlusal caries were included in this study. The occlusal surface of each tooth was scored using DDPen and ICDAS II scoring before remineralisation. Then, remineralisation of the teeth of the experimental group was carried out using either CPP-ACP-F or fluoride varnish. After the remineralisation procedures, the occlusal surface of each tooth was again scored using DDPen and ICDAS II scoring. The teeth were then fixed in dental stone blocks and sectioned longitudinally for histological examination using a stereomicroscope. Statistical analysis was performed to calculate the sensitivity and specificity of DDPen and ICDAS II to detect remineralisation and compare with the gold standard histological examination. Results. According to ICDAS-II scores, a significant difference was noted in GC Tooth Mousse Plus® and Duraphat® study samples, whereas the difference between the pre-and post-remineralisation of the control group was not significant. According to the DDPen score criteria, a statistically significant difference was noted among all study groups; however, a greater significance level was noted in the GC Tooth Mousse Plus® and Duraphat® study samples compared with the control group. The Spearman’s rank correlation of ICDAS-II and DDPen with Downer’s histological score (gold standard) revealed a higher association of DDPen score (.738) as compared to ICDAS-II scores (.430). Conclusion. The study concluded that both ICDAS II and DDPen could detect remineralisation of early enamel occlusal caries. DDPen was more sensitive than ICDAS-II to detect remineralisation compared with the Downers histological scores.

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Section: Discussionmentioning

confidence: 71%

Effectiveness of Visual-Tactile Examination and DIAGNOdent Pen in Detecting Early Enamel Caries and Its Remineralisation: An In Vitro Study

Rashid

Karobari

Halim

et al. 2022

BioMed Research International

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“…6 Difluorosilane juga memiliki jumlah retensi fluoride yang tinggi pada gigi dan dapat bergabung dengan plak untuk menghambat pertumbuhan bakteri dan mereduksi pembentukan asam laktat yang menurunkan pH di rongga mulut. 7 Namun, penggunaan 0,9% Difluorsilane di klinik lebih rendah dibandingkan Sodium fluoride (NaF) karena efektivitas kariogenik dari Difluorosilane yang lebih rendah. 8 Sodium fluoride (NaF) merupakan salah satu bahan fluoride varnish yang banyak digunakan.…”

Section: Pendahuluanunclassified

“…Kandungan silane pada Difluorosilane 0,9% memiliki efek antibakterial yang mampu mengurangi jumlah bakteri pada plak dan saliva dan mereduksi pembentukan asam laktat. 7,14,15 Menurut Erdem dkk (2012) dan Sharma dkk (2018) aplikasi Difluorosilane 0,9% dapat menurunkan jumlah bakteri Streptococcus mutans pada plak dan saliva, sehingga produksi asam akan menurun dan terjadi peningkatan pH plak dan pH saliva. 14,15 Kandungan Sodium fluoride dan Tricalcium phosphate pada kombinasi Sodium fluoride 5% dengan Tricalcium phosphate juga dapat mempengaruhi peningkatan pH plak dan pH saliva.…”

Section: Pembahasanunclassified

Perbandingan Difluorosilane 0,9% Dan Kombinasi Sodium Fluoride 5% Dengan Tricalcium Phosphate Terhadap Perubahan Ph Plak Dan Ph Saliva Anak

Sofrullah¹,

Dewi²,

Puspitasari³

2021

Dentin

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Background: Low water acidity (pH) in wetland area can cause caries by decreasing plaque pH and salivary pH. The usage of Difluorosilane and combination of Sodium fluoride with Tricalcium phosphate can prevent caries. Objective: to compare Difluorosilane 0.9% and combination of Sodium fluoride 5% with Tricalcium phosphate on plaque pH and salivary pH changes in children at Barito Kuala. Method: This study was true experimental with total sample were 12 people who were divided into 3 groups. Plaque and saliva samples were measured before application and 1 hour after application using a pH meter. Results: One-Way ANOVA and Post Hoc Bonferroni test results indicated that there is significant differences(p<0,05) in plaque pH and salivary pH changes between Difluorosilane 0.9% group, combination of Sodium fluoride 5% with Tricalcium phosphate group, and control group. Plaque pH and salivary pH changes in Difluorosilane 0.9% group is (0,03±0,088) and (0,01±0,063), combination of Sodium fluoride 5% with Tricalcium phosphate group is (0,16±0,044) and (0,09±0,060), control group is (-0,09±0,021) and (-0,10±0,029). Conclusion: Combination of Sodium fluoride 5% with Tricalcium phosphate can increase plaque pH and salivary pH greater than Difluorosilane 0.9% for children aged 7-9 years at Barito Kuala.Keywords: Difluorosilane, Plaque pH, Salivary pH, Sodium fluoride, Tricalcium phosphate, wetlandABSTRAKLatar belakang: Penggunaan air dengan pH yang rendah pada lahan basah dapat menyebabkan karies melalui penurunan pH plak dan pH saliva. Pencegahan karies dapat dilakukan dengan penggunaan Difluorosilane dan kombinasi Sodium fluoride dengan Tricalcium phosphate. Tujuan: membandingkan Difluorosilane 0,9% dan kombinasi Sodium fluoride 5% dengan Tricalcium phosphate terhadap perubahan pH plak dan pH saliva pada anak di Kabupaten Barito Kuala. Metode: Penelitian ini menggunakan metode penelitian True Eksperimental dengan sampel sebanyak 12 orang yang dibagi menjadi 3 kelompok. Sampel plak dan saliva dilakukan pengukuran menggunakan pH meter pada saat sebelum aplikasi dan 1 jam setelah aplikasi. Hasil: Hasil uji One-Way ANOVA dan Post Hoc Bonferroni menyatakan terdapat perbedaan perubahan pH plak dan pH saliva yang bermakna (p<0,05) antara kelompok aplikasi Difluorosilane 0,9%, aplikasi kombinasi Sodium fluoride 5% dengan Tricalcium phosphate, dan tanpa perlakuan. Perubahan pH plak dan pH salivap pada aplikasi Difluorosilane 0,9% yaitu (0,03±0,088) dan (0,01±0,063), aplikasi kombinasi Sodium fluoride 5% dengan Tricalcium phosphate yaitu (0,16±0,044) dan (0,09±0,060), serta tanpa perlakuan yaitu (-0,09±0,021) dan (-0,10±0,029). Kesimpulan: Aplikasi kombinasi Sodium fluoride 5% dengan Tricalcium phosphate dapat meningkatan pH plak dan pH saliva lebih besar dibandingkan dengan aplikasi Difluorosilane 0,9% pada anak usia 7-9 tahun di Kabupaten Barito Kuala.Kata kunci: Difluorosilane, lahan basah, pH plak, pH saliva, Sodium fluoride, Tricalcium phosphate.

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“…Oral cavity is dominated by cariogenic bacterial and fungal species like Candida albicans (1). Candida albicans (non-specific plaque hypothesis) causes fermentation of the dietary carbohydrates leading to the formation of organic acids which causes a decrease in pH leading to dissolution of the inorganic contents of the tooth (2) and thereby contributing to the development of carious tooth (3) Various approaches have been introduced to reduce the occurrence of dental caries. (2) Fluoride varnish which is immune to dental caries was first reported back in in Europe in 1964.…”

Section: Introductionmentioning

confidence: 99%

“…Candida albicans (non-specific plaque hypothesis) causes fermentation of the dietary carbohydrates leading to the formation of organic acids which causes a decrease in pH leading to dissolution of the inorganic contents of the tooth (2) and thereby contributing to the development of carious tooth (3) Various approaches have been introduced to reduce the occurrence of dental caries. (2) Fluoride varnish which is immune to dental caries was first reported back in in Europe in 1964. (4) Flour protector, originally developed by Arends and Schuthof in 1975 with a fluoride concentration of 0.7 % Ethyl acetate, Difluorosilane (0.9 %)-active ingredient, contains 7,700 ppm at application.…”

Section: Introductionmentioning

confidence: 99%

Comparative Evaluation of Effect of Different Varnishes (MI Varnish, Clinpro Varnish and Fluor Protector Varnish) on Candida albicans Count and Salivary pH in Children aged 6-12 years – A Randomized Control Trial

JR¹,

Gupta²,

Gambhir³

et al. 2022

Journal of Pharmaceutical Negative Results

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PURPOSE: Candida albicans one of the commensal organisms in the oral cavity, causes fermentation of the dietary carbohydrates leading to the formation of organic acids, which contributes to the development of dental caries. The aim of the study was to evaluate and compare the efficacy of 3 different fluoride varnishes against Candida albicans in the prevention of dental caries before and immediately after fluoride varnish application and also over a period of 1 week, 1 month and 3 months. METHODOLOGY: A sample size of 60 children’s aged between 6-12 years were randomly selected by block randomization and divided into 3 groups: Group 1 MI Varnish, Group 2 Clinpro XT varnish and Group 3 Flour Protector varnish. Unstimulated saliva samples were collected before and after the application of fluoride varnishes (collected immediately after application, after 1 week, 1 month and 3 months) and were sent for microbiological analysis. The pH of the samples were evaluated by Indikrom paper strips. The results obtained were statistically analysed by mean, standard deviation and One way ANOVA. RESULTS: MI varnish showed a significant drop in Candida albicans followed by Clinpro XT varnish and Fluor Protector Varnish whereas no significant difference were seen in pH. CONCLUSION: The results of the study shows that MI Varnish, Clinpro XT Varnish and Fluor Protector Varnish have antifungal effect on Candida albicans. MI Varnish showed its more profound effect.

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Effect of three different compositions of topical fluoride varnishes with and without prior oral prophylaxis on Streptococcus mutans count in biofilm samples of children aged 2–8 years: A randomized controlled trial

Cited by 12 publications

References 15 publications

Effectiveness of Visual-Tactile Examination and DIAGNOdent Pen in Detecting Early Enamel Caries and Its Remineralisation: An In Vitro Study

Effectiveness of Visual-Tactile Examination and DIAGNOdent Pen in Detecting Early Enamel Caries and Its Remineralisation: An In Vitro Study

Perbandingan Difluorosilane 0,9% Dan Kombinasi Sodium Fluoride 5% Dengan Tricalcium Phosphate Terhadap Perubahan Ph Plak Dan Ph Saliva Anak

Comparative Evaluation of Effect of Different Varnishes (MI Varnish, Clinpro Varnish and Fluor Protector Varnish) on Candida albicans Count and Salivary pH in Children aged 6-12 years – A Randomized Control Trial

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