Effect of Timing and Duration of Tamsulosin Exposure on Complications in Resident-Performed Phacoemulsification

Ku, Tina K; Naseri, Ayman; Han, Ying; Porco, Travis C.; Rutar, Tina

doi:10.3928/15428877-20110602-01

Cited by 5 publications

(1 citation statement)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Second, we were unable to confirm whether the recorded eye with complications was the same eye that underwent cataract surgery, but we minimize the error by using a short follow-up period for complications. Moreover, we do not know precisely how long patients took tamsulosin before cataract surgery, but some studies 20,21 report that the duration of treatment was not a significant factor for cataract surgery-related complications. In addition, because multiple outcomes were examined in this study, false-positives may be a concern.…”

Section: Discussionmentioning

confidence: 98%

Wound Dehiscence as a Cataract Surgery–Associated Postoperative Complication in Patients Previously Treated With Alpha-1 Blocker Tamsulosin—A Population-Based Study in Taiwan

Hsiao

Liao

et al. 2014

American Journal of Ophthalmology

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 98%

Wound Dehiscence as a Cataract Surgery–Associated Postoperative Complication in Patients Previously Treated With Alpha-1 Blocker Tamsulosin—A Population-Based Study in Taiwan

Hsiao

Liao

et al. 2014

American Journal of Ophthalmology

View full text Add to dashboard Cite

Tamsulosin

2016

Meyler's Side Effects of Drugs

View full text Add to dashboard Cite

Antihypertensive drugs

Coleman¹,

Cox²

2014

A Worldwide Yearly Survey of New Data in Adverse Drug Reactions and Interactions

View full text Add to dashboard Cite

Updated guidance on the management of hypertension in adults in the UK offers new advice, including recommendations on the treatment of very elderly people (over 80 years old), who should be offered the same treatment as patients aged 55-80 years, while taking into account co-morbidities [1 S ]. Previous guidance has acknowledged that while elderly people may accrue benefits from lowering of blood pressure, treatment could potentially lead to more adverse events, such as syncope and falls. However, the most recent evidence challenges this position. Other useful recommendations consider the risk of adverse drug reactions in therapy; for example, the recommendation that patients should not have a combination of an angiotensin converting enzyme (ACE) inhibitor and an angiotensin II receptor antagonist to treat hypertension, based on trial evidence of increased rates of adverse events with this treatment combination. Furthermore, in view of the propensity for black people of African or Caribbean family origin to develop angioedema from ACE inhibitors, angiotensin II receptor antagonists should be used in preference to ACE inhibitors.Reviews of the pharmacotherapy of chronic pediatric hypertension [2 R ] and the management of hypertension in pregnancy [3 R ] have also been published.Nervous system The risk of falls associated with various antihypertensive drug classes has been studied in a self-controlled case series using The Health Improvement Network primary care database in the UK [4 C ]. The researchers analysed 9862 individuals over 60 years of age and estimated incidence rate ratios for falls during periods of exposure and non-exposure adjusted for age. The highest incidence rate ratio for first fall within 3 weeks of medication use was with thiazide diuretics (IRR ¼ 2.80; 95% CI ¼ 1.70, 4.57). Beta-adrenoceptor antagonists were associated with an increased incidence of falls from day 22 onwards in the first episode of medication (IRR ¼ 1.23; 95% CI ¼ 1.02, 1.48) and in subsequent episodes (IRR ¼ 1.21; 95% CI ¼ 1.02, 1.42). The implications of this analysis, given the usual limitations of prescription database research, insofar as what is recorded may not always reflect actual exposure, is that clinicians who issue prescriptions of thiazide diuretics for older people should be alert to the possibility of an increased risk of falls early in therapy.Musculoskeletal Some antihypertensive drugs are associated with changes in bone metabolism. A large prospective cohort study of hypertensive patients beginning treatment with a single antihypertensive drug has therefore been conducted using health-care utilization data to determine the risk of a typical osteoporotic fracture [5 C ]. The fracture rate in the cohort of 376 061 patients was on average 35 fractures per 1000 patient-years, but rates varied across antihypertensive drug classes. When adjusted for co-morbidities and comedications, the fracture risk was reduced for angiotensin receptor blockers (HR ¼ 0.76; 95% CI ¼ 0.68, 0.86) and thiazide diuretics (HR ¼ 0.85...

show abstract

Effect of Timing and Duration of Tamsulosin Exposure on Complications in Resident-Performed Phacoemulsification

Abstract: The authors were unable to detect a statistically significant effect of duration of tamsulosin use on the risk of intraoperative complications in phacoemulsification surgery.

Cited by 5 publications

References 33 publications

Wound Dehiscence as a Cataract Surgery–Associated Postoperative Complication in Patients Previously Treated With Alpha-1 Blocker Tamsulosin—A Population-Based Study in Taiwan

Wound Dehiscence as a Cataract Surgery–Associated Postoperative Complication in Patients Previously Treated With Alpha-1 Blocker Tamsulosin—A Population-Based Study in Taiwan

Tamsulosin

Antihypertensive drugs

Contact Info

Product

Resources

About