Effect of Toothbrushing with Different Concentrations of Chlorhexidine on the Development of Dental Plaque and Gingivitis

Bay, Lena M.

doi:10.1177/00220345780570020401

Cited by 20 publications

(14 citation statements)

References 10 publications

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“…which showed that the addition of fiuoride to a chiorhexidine solution did not adversely affect its antiplaque action. The results of the present study also agree with those of previous workers who showed that a concentration of chjorhexidine as low as 0,05 per cent can be effective in helping to prevent piaque deposition (Bay 1978, Bonesvol! 1978 and gingival inflammation (Bay 1978, Luoma et al 1978).…”

Section: Discussionsupporting

confidence: 92%

“…The results of the present study also agree with those of previous workers who showed that a concentration of chjorhexidine as low as 0,05 per cent can be effective in helping to prevent piaque deposition (Bay 1978, Bonesvol! 1978 and gingival inflammation (Bay 1978, Luoma et al 1978). In the present study, as in previous studies (Bay 1978, Bonesvoli 1978, Luoma et al 1978, plaque was not completely inhibited, nor was gingival infiammation completely prevented.…”

Section: Discussionsupporting

confidence: 92%

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The effect of a mouthrinse containing chlorhexidine and fluoride on plaque and gingival bleeding

Joyston-Bechal

Hernaman

1993

J Clinic Periodontology

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The aim of this study was to test the effect of a rinse with 0.05% sodium fluoride and 0.05% chlorhexidine on plaque and gingival inflammation compared with a placebo without these agents. In a double-blind study, 47 adults with > 20 teeth and a CPITN score > 1 but < 4 were randomised into test and control groups. After baseline assessments for plaque, bleeding and stain, teeth were professionally cleaned. Subjects were asked to rinse for 30 s with 10 ml of the respective test or placebo rinse after normal oral hygiene for 8 weeks. 39 subjects completed the study. There was no significant difference in the 2 groups at baseline with respect to either plaque or bleeding scores. After scaling and 8 weeks use of the test rinse, there were significant reductions (p < 0.001) in both plaque and bleeding. The control group showed no significant reduction in plaque scores after 8 weeks, but a significant (p < 0.05) reduction in bleeding. However, this reduction was significantly greater (p < 0.001) in the test group than in the control. The test group had a significantly greater (p < 0.05) stain score than the control at baseline. After scaling and rinsing for 8 weeks, stain scores were lower for both groups compared to baseline but reached significance (p < 0.05) only for the control group. It is concluded that, as an adjunct to normal oral hygiene, the chlorhexidine/fluoride rinse had a significant inhibitory effect on plaque and bleeding but its effect on staining is uncertain.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 92%

The effect of a mouthrinse containing chlorhexidine and fluoride on plaque and gingival bleeding

Joyston-Bechal

Hernaman

1993

J Clinic Periodontology

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“…Indeed, many studies have demonstrated that 0.1 % and 0.12 % CLX mouthrinse have a significant comparable effect on plaque reduction as 0.2 % CLX formulation (9-12). …”

Section: Introductionmentioning

confidence: 99%

Chlorhexidine alcohol base mouthrinse versus Chlorhexidine formaldehyde base mouthrinse efficacy on plaque control: Double blind, randomized clinical trials

Ennibi¹,

Lakhdar²,

Bouziane³

et al. 2013

Med Oral

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Background: Chlorhexidine is well known for its antiplaque effect. However, the mouthrinse based chlorhexidine antiplaque efficiency may vary according to the formulation of the final product. The aim of the present study was to compare anti-plaque effectiveness of two commercial mouthrinses: 0.12 % Chlorhexidine alcohol base (CLX-A) versus a diluted 0.1% Chlorhexidine non-alcohol base with 0.1% of Formaldehyde (CLX-F). Material and Methods: the study was a seven day randomized, double-blind, placebo-controlled trial including 30 volunteers. At the start, all participants received a dental prophylaxis. Over 7 days experimental non-brushing period, during which subjects abstained from all forms of mechanical oral hygiene, one group test rinsed twice daily with 15ml of an alcohol base 0.12% Chlorhexidine mouthrinse. The second group test used 15ml of alcohol free 0.1% Chlorhexidine mouthrinse base 0.1% formaldehyde twice daily. The negative control group used a placebo. Plaque indexes were recorded in all volunteers prior to treatment at Day 0, 1 and 7. Results: After 7 days, the mean plaque index for the first group was 0.76±0.38 compared with a mean plaque index of 1.43±0.56 for the second group. The difference in plaque scores between the groups was statistically significant. Conclusion: the results of this study showed that rinsing with an alcohol base 0.12% Chlorhexidine mouthrinse is significantly different from rinsing with an alcohol free 0.1% Chlorhexidine mouthrinse on plaque inhibition. Key words:Chlorhexidine, dental plaque, mouthrinse, alcohol, formaldehyde.

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“…6 A lower concentration of CHX (0.12%) has been tested in animals and human populations and has also demonstrated clinical benefits. 7,13,14 Although CHX is an effective antimicrobial agent in both concentrations, comparison of the two existing formulations is still necessary. The aim of the present study was to assess the efficacy of two concentrations of chlorhexidine solutions (0.12% and 0.20%) on plaque development and gingival bleeding control during 14 days.…”

mentioning

confidence: 99%

Comparative analysis of the effect of two chlorhexidine mouthrinses on plaque accumulation and gingival bleeding

Neto¹,

Parolo²,

Rösing

et al. 2008

Braz. oral res.

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The aim of the present study was to evaluate the effect of two chlorhexidine rinsing solutions (0.12% and 0.2%) on plaque and gingival bleeding. Ten dental students participated in this double-blind, cross-over study, rinsing twice a day, for one minute, with each one of the tested solutions for fourteen days. A wash-out period of one week between treatments was observed. In order to assess gingival bleeding, the van der Weijden et al. 1 (1994) index was used. The plaque indexes used were those of Quigley, Hein 2 (1962) and Silness, Löe 3 (1964). In the pre-experimental period, subjects received oral hygiene instructions and dental prophylaxis. The results revealed no significant differences between both concentrations in relation to plaque and gingival bleeding. Mean values (± standard deviation) of the Quigley & Hein index were 0.25 ± 0.16 for the 0.12% solution and 0.23 ± 0.26 for the 0.2% solution (p = 0.4838). Mean values (± standard deviation) of the Silness-Löe index were 0.12 ± 0.10 for the 0.12% solution and 0.11 ± 0.11 for the 0.2% solution (p = 0.7592). The bleeding index mean values at the end of the study were not different for both concentrations with mean values (± standard deviation) of 14.93% ± 6.68% and 13.95 ± 9.24% for the 0.12% and 0.2% solutions, respectively. Although an increase in gingival bleeding was observed, both concentrations were able to control dental plaque.

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Effect of Toothbrushing with Different Concentrations of Chlorhexidine on the Development of Dental Plaque and Gingivitis

Cited by 20 publications

References 10 publications

The effect of a mouthrinse containing chlorhexidine and fluoride on plaque and gingival bleeding

The effect of a mouthrinse containing chlorhexidine and fluoride on plaque and gingival bleeding

Chlorhexidine alcohol base mouthrinse versus Chlorhexidine formaldehyde base mouthrinse efficacy on plaque control: Double blind, randomized clinical trials

Comparative analysis of the effect of two chlorhexidine mouthrinses on plaque accumulation and gingival bleeding

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