Effect of Treadmill Training and Supramalleolar Orthosis Use on Motor Skill Development in Infants With Down Syndrome: A Randomized Clinical Trial

Looper, Julia; Ulrich, Dale A.

doi:10.2522/ptj.20090021

Cited by 40 publications

(58 citation statements)

References 19 publications

(17 reference statements)

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“…Upon withdrawal of BWSTT, but with continued PT intervention, achieved gains in GMFM-E scores were maintained at the 6-week follow-up. Our findings are consistent with those seen in children with DS, (a group similar in muscle tone, skill development, gait speed, and onset of ambulation), who exhibited improved scores on pediatric developmental motor tests such as the GMFM, 24–25 and improved gait velocity, 22 following BWSTT.…”

Section: Discussionsupporting

confidence: 88%

“…randomized control trials) evidence is available that suggests BWSTT will hasten the onset of walking as well as motor milestone achievement in children with DS. 22–25 Additionally, the literature in the DS population has explored the effects between a generalized low intensity (LG) and a high intensity individualized (HI) BWSTT program in a series of studies using the same cohort. A series of studies in the DS population were performed and suggest that HI training in particular, facilitates significant improvements in stride length leading to a more mature gait pattern, 22 earlier motor milestone achievement, 24 increased stepping, 24 and earlier onset of walking.…”

Section: Introduction and Purposementioning

confidence: 99%

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Body Weight Support Treadmill Training for Children With Developmental Delay Who Are Ambulatory

Lowe

McMillan

Yates

2015

Pediatric Physical Therapy

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Purpose To examine the effect of body weight supported treadmill training (BWSTT) on gait and gross motor skill development in children (2–5 years old) with developmental delay who are ambulatory. Methods Twenty-four subjects (12 control, 12 BWSTT) were enrolled in this randomized control trial. All subjects continued to receive physical therapy. Subjects were tested at baseline, 4 weeks, 6 weeks, and at 6 weeks following completion of BWSTT. Outcomes were assessed using the 10 Meter Walk Test (10MWT) and Gross Motor Function Measure- D and E. Results Significant improvements were seen in gait velocity and gross motor skill attainment. With positive interactions in both the 10MWT and GMFM-E, the BWSTT group as compared to the control group demonstrated functional gains in gait velocity and gross motor skills, P = .033 and.017, respectively. Conclusions A 6-week high intensity BWSTT program can improve gait velocity and influence functional gains.

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Section: Discussionsupporting

confidence: 88%

Section: Introduction and Purposementioning

confidence: 99%

Body Weight Support Treadmill Training for Children With Developmental Delay Who Are Ambulatory

Lowe

McMillan

Yates

2015

Pediatric Physical Therapy

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“…), early intervention techniques, such as infant massage (Hernandez‐Reif et al . ) or neurodevelopment therapy (Harris ), and orthotic devices, such as the supramalleolar orthosis (Looper & Ulrich ; Looper & Ulrich ).…”

Section: Resultsmentioning

confidence: 99%

“…That is the case of three studies (Ulrich et al . ; Looper & Ulrich ; Looper & Ulrich ) in which the intervention ended when the subject acquired the ability to walk. The frequency of the intervention ranged from only 1 day (Chen et al .…”

Section: Resultsmentioning

confidence: 99%

Physical therapy in Down syndrome: systematic review and meta‐analysis

Ruiz-González

Lucena-Antón

Salazar

et al. 2019

J intellect Disabil Res

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Background Down syndrome is the most common chromosomal abnormality, with a worldwide incidence of around 0.1% in live births. It is related to several conditions in which the physical therapy could take action‐preventing co‐morbidities. This study aims to evaluate the effectiveness of physical therapy in Down syndrome, to know and compare the effectiveness of different physical therapy interventions in this population. Methods A systematic review and a meta‐analysis of randomised controlled trials were conducted. The search was performed during June 2018 in the following databases: PubMed, Web of Science, Physiotherapy Evidence Database and Scopus. The studies were selected using predefined inclusion and exclusion criteria. The Physiotherapy Evidence Database scale evaluated the quality of the methods used in the studies. Subsequently, the data were extracted, and statistical analysis was performed when possible. Results A total of 27 articles were included, of which nine contributed information to the meta‐analysis. Statistical analysis showed favourable results for the strength of upper and lower limbs [standardised mean difference (SMD) = 1.46; 95% confidence interval (CI): (0.77–2.15); and SMD = 2.04; 95% CI: (1.07–3.01)] and mediolateral oscillations of balance [SMD = −3.30; 95% CI: (−5.34 to −1.26)]. Conclusions The results show the potential benefit of certain types of physical therapy interventions, specifically in strength and balance, in people with Down syndrome. There are still many aspects to clarify and new lines of research.

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“…Partial unweighting allows the child to practice walking safely at a faster, more typical pace Appears to be highly effective with infants having Down syndrome (Looper & Ulrich, 2010 ;Ulrich, Lloyd, Tiernan, Looper, & Angulo-Barroso, 2008 ;Ulrich, Ulrich, Angulo-Kinzler, & Yun, 2001 ). Study participants walked on average 100 days (3 months) earlier than controls without treadmill training.…”

Section: Constraint-induced Movement Therapymentioning

confidence: 99%

Handbook of Early Childhood Special Education

Reichow

Boyd

Barton

et al. 2016

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Effect of Treadmill Training and Supramalleolar Orthosis Use on Motor Skill Development in Infants With Down Syndrome: A Randomized Clinical Trial

Abstract: Orthoses may have a detrimental effect on overall gross motor skill development.

Cited by 40 publications

References 19 publications

Body Weight Support Treadmill Training for Children With Developmental Delay Who Are Ambulatory

Body Weight Support Treadmill Training for Children With Developmental Delay Who Are Ambulatory

Physical therapy in Down syndrome: systematic review and meta‐analysis

Handbook of Early Childhood Special Education

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