Effect of trehalose supplementation on growth performance and intestinal morphology in broiler chickens

Ruangpanit, Y.; Matsushita, Koichi; Mukai, Kazuhisa; Kikusato, Motoi

doi:10.1016/j.vas.2020.100142

Cited by 10 publications

(14 citation statements)

References 26 publications

(32 reference statements)

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“…The health and morphology of the intestinal tract of birds are easily affected by the environment and environmental conditions [25]. The present study measured intestinal morphological parameters such as VH, CD and VCR, as they are frequently used as indicators of nutrient absorption and growth performance in hens [26]. A larger VH and VCR in the small intestine as well as a larger VCR in the caecum were observed in the NRS group.…”

Section: Discussionmentioning

confidence: 71%

Effects of Different Non-Cage Housing Systems on the Production Performance, Serum Parameters and Intestinal Morphology of Laying Hens

Wan

Yang

Zhang³

et al. 2021

Animals

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This study investigated the effects of plastic-net housing system (NRS) and floor-litter housing system (LRS) on the production performance, serum parameters and intestinal morphology of Shendan laying hens. A total of 1200 30-week-old hens were randomly allocated to the NRS and LRS groups, each of which included five replicates with 120 chickens in each replicate. The experiment was conducted from 32 to 40 weeks of age. Indoor airborne parameters were measured every 2 weeks, and indoor ground contamination was measured monthly. The laying rate and mortality of hens were recorded daily, and egg quality traits and serum parameters were measured every 2 weeks. At 40 weeks of age, four birds per replicate from each experimental group were selected for intestinal morphological observation. The results showed that the airborne bacteria number in the LRS was significantly higher than that in the NRS (p < 0.05) for most of the experimental period (except at 32 and 38 weeks of age), and the bacterial numbers on the surfaces of the floor and floor eggs in the LRS were approximately 10 times higher than those in the NRS (p < 0.05). Compared with the LRS, the NRS improved the laying rate (p < 0.05), reduced serum malondialdehyde (MDA) (p < 0.05) and corticosterone (CORT) concentrations and increased serum glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) activities, indicating favourable effects on antioxidative status. The NRS was significantly associated with an increased villus height (VH), villus height to crypt depth ratio (VCR) in the small intestine (p < 0.05) and increased VCR in the caecum (p < 0.05). Overall, the lower rate of bacterial contamination in the NRS than in the LRS indicated better environmental hygiene. The NRS enhanced the laying performance and antioxidant capacity of hens and was superior to the LRS in improving intestinal health. The current findings support the advantages of the NRS for the health and welfare of Shendan chickens during the peak laying period.

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Section: Discussionmentioning

confidence: 71%

Effects of Different Non-Cage Housing Systems on the Production Performance, Serum Parameters and Intestinal Morphology of Laying Hens

Wan

Yang

Zhang³

et al. 2021

Animals

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“…The histomorphometry of duodenum, jejunum, and ileum of the chickens at 21 days of age are presented in Table 4. For a healthy chicken, villus height/crypt depth (VH:CD) ratio is expected to be at least 5 (five parts of villus per one part of crypt) [30], as observed in G1. Epithelial sloughing was observed in non-treated challenged chickens (G2) and treated with blank formulation (LNC, G7).…”

Section: Histomorphometric Measurements Of the Small Intestinementioning

confidence: 99%

“…For this purpose, the formulations were aliquoted in amber glass vials (two for each condition) and kept at room temperature (20 • C) or under refrigeration (8 • C). At different time intervals (1,7,15,30, and 60 days), samples were collected based on two different procedures: one vial was kept at rest while the other was homogenized before pipetting. Afterwards, samples were quantified by HPLC, as previously described.…”

Section: Evaluation Of the Presence Of Nanocrystalsmentioning

confidence: 99%

Toltrazuril-Loaded Polymeric Nanocapsules as a Promising Approach for the Preventive Control of Coccidiosis in Poultry

et al. 2022

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Coccidiosis is a disease caused by intracellular protozoan parasites of the genus Eimeria that affect the intestinal tract of poultry. However, strain resistance and drug residue in the carcass have drawn the attention of the productive sector. The nanotechnology can improve the biological effect of drugs, reducing of administered doses and toxic effects. Due to this, toltrazuril-load polymeric nanoparticles based on Eudragit® S100 (NCt) or poly-ε-caprolactone (LNCt) were developed to prevent coccidiosis in broilers. Nanoformulations were produced and showed homogeneous particle diameter distribution in the nanometer range (z-average and D (4.3) < 200 nm), negative zeta potential (<−8.93 mV), drug content ~100%, and encapsulation efficiency >90%. Cell viability assays using avian fibroblasts showed that LNCt presented no relevant toxicity up to 72 h. LNCt was then prophylactically administrated to chicken followed by challenge with Eimeria oocysts. The evaluation of the small intestine and cecum showed that the treatment with LNCt (3.5 mg/kg/day) in drinking water reduced the lesion scores and oocysts excretion, similar to the reference medicine containing toltrazuril (Baycox®, 7 mg/kg/day). The current study shows the potential protective use of nanoencapsulating anticoccidial drugs as a promising approach for the control of coccidiosis in poultry.

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“…Literature suggests that a greater VH/CD ratio was associated with the broiler's increased capacity to absorb the nutrients deriving from the digestion process (Ruangpanit et al, 2020). In this study, the duodenum and ileum of additive-administrated broilers showed a higher VH ratio to CD than that of control, suggesting that the additive could improve the intestinal function in absorbing the nutrients.…”

Section: Intestinal Morphology Of Broilersmentioning

confidence: 49%

Blood and Intestine Profile of Broilers Fed Averrhoa bilimbi Fruit, Wheat Bran, and Yeast Blends

Pratama

Yudiarti

Sugiharto

et al. 2022

Trop. Anim. Sci. J.

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A. bilimbi fruit filtrate, wheat bran, and S. cerevisiae contain bioactive components favorable to broiler health. The use of these compounds in combination was expected to exert synergistic effects on broilers. The study investigated the effect of a combination of A. bilimbi fruit filtrate, wheat bran, and S. cerevisiae on haematological indices and intestinal selected bacteria and morphology of broilers. A total of 280 broiler chicks were randomly divided into 4 groups with 7 replications, including CONT (chicks offered diet without additive), TBLEND1, BLEND2, and BLEND3 (chicks offered diet with 0.25%, 0.5%, and 1% of the additive combination of A. bilimbi fruit filtrate, wheat bran, and S. cerevisiae]), respectively. For data collection, the chicks were blood sampled at day 21 and 35, and slaughtered at day 35. The data were statistically treated with analysis of variance according to a completely randomized design. On day 21, the erythrocytes and haemoglobin levels were lower in BLEND2 and BLEND3 than those in CONT and BLEND1 (p<0.05). The leukocytes and lymphocytes values were lower in BLEND2 and BLEND3 than those in CONT (p<0.05). On day 35, erythrocytes were lower (p<0.05) in BLEND3 than that in CONT and BLEND1. The increased additive levels linearly decreased (p<0.05) erythrocytes, haemoglobin, and haematocrits values. At day 21, total triglyceride was lower (p<0.05) in BLEND3 than that in BLEND1 and BLEND2. The LDL level was lower (p<0.05) in BLEND3, whereas the HDL level was higher (p<0.05) in CONT than that in other groups. Creatinine was higher (p<0.05) in BLEND3 than in other groups. The ileal lactose negative Enterobacteriaceae counts were lower in BLEND1, BLEND2, and BLEND3 than in CONT (p<0.05). The duodenal villi height to crypt depth ratio (VH/CD ratio) was higher (p<0.05) in BLEND1 than that in CONT and BLEND2. In the ileum, the VH/CD ratio linearly increased (p<0.05) with the elevated additive levels. In conclusion, the combination of A. bilimbi fruit filtrate, wheat bran, and S. cerevisiae was beneficial in reducing intestinal pathogen load and improving intestinal morphology of broilers.

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Effect of trehalose supplementation on growth performance and intestinal morphology in broiler chickens

Abstract: Highlights Trehalose improved intestinal morphology. Trehalose improved broiler growth performance without antibiotics. Trehalose's effects may depend on feeding conditions.

Cited by 10 publications

References 26 publications

Effects of Different Non-Cage Housing Systems on the Production Performance, Serum Parameters and Intestinal Morphology of Laying Hens

Effects of Different Non-Cage Housing Systems on the Production Performance, Serum Parameters and Intestinal Morphology of Laying Hens

Toltrazuril-Loaded Polymeric Nanocapsules as a Promising Approach for the Preventive Control of Coccidiosis in Poultry

Blood and Intestine Profile of Broilers Fed Averrhoa bilimbi Fruit, Wheat Bran, and Yeast Blends

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