Effect of Ultraviolet Light on the Sulfhydryl and Disulfide Concentration in Living Human Epidermis

Ogura, Ryohei; Knox, John M.

doi:10.1159/000254768

Cited by 8 publications

(1 citation statement)

References 8 publications

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“…A number of biochemieal changes occur following UVL irradiation. By microamperometric assessments of the whole epidermis, i transient increase in amounts of S-S bondsi and a decrease in amounts of -SH groups were deteeted during one to three days postirradiation (Kusuhara & Knox 1962, Ogura & Knox 1964. Sueh changes in -SH and S-S groups are likely to occur in sunburn cells.…”

Section: Sunburn Cettmentioning

confidence: 99%

Sulphhydryl crosslinking in cutaneous apoptosis: A review

Danno¹,

Horio²

1982

J Cutan Pathol

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Histochcmical findings of cutaneous apoplosis arc reviewed with special reference to the sulphhydryl groups. Using stain techniques with the new fluorescent thiol reagent, N-(7-diniethylamino-4-mcthylcoumarinyl) nialcimide (DACM), it was shown that sulphhydryl crosslinking occurs in colloid bodies and sunburn cells and also participates, at least in part, in amyloid formation. As the DACM staining clearly demonstrated the localization of sulphhydryl and disulphidc groups in the epidermis, this technique can be of help dealing with the problem of the origin of cutaneous apoptotic bodies.

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Section: Sunburn Cettmentioning

confidence: 99%

Sulphhydryl crosslinking in cutaneous apoptosis: A review

Danno¹,

Horio²

1982

J Cutan Pathol

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Lichtbiologie der Haut

Jung¹,

Bohnert²

1979

Normale Und Pathologische Physiologie Der Haut II

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Induced pemphigus

Ruocco¹,

Pisani²

1982

Arch Dermatol Res

119

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The reports of induced pemphigus have multiplied over the last 10 years. Several heterogeneous factors, such as drugs (penicillamine, pyritinol, captopril, rifampicin, etc.), physical agents (burns, UV, and ionizing radiation) and viruses, can play an inducing role. Usually, the disease is preceded by prodromal, non-specific lesions. The full-blown stage shows features of pemphigus foliaceus, erythematosus or herpetiformis. Histologically, acantholytic splits mostly occur at the highest malpighian layers. Intercellular antibodies and frequently concomitant other auto-antibodies are found in the serum, the titre of the former usually being low and unrelated to the severity or course of the disease. The biological progress is variable and ranges from rapidly and definitively healing cases (induced pemphigus proper) to others which, in spite of the elimination of the inducing factor, self perpetuate just like true pemphigus (triggered pemphigus). Pathogenic hypotheses are based on the act that some inducing factors can alter the antigen distribution on keratinocyte membranes and/or interfere with immune surveillance by impairing T-suppressor cells.

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Effect of Ultraviolet Light on the Sulfhydryl and Disulfide Concentration in Living Human Epidermis

Cited by 8 publications

References 8 publications

Sulphhydryl crosslinking in cutaneous apoptosis: A review

Sulphhydryl crosslinking in cutaneous apoptosis: A review

Lichtbiologie der Haut

Induced pemphigus

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