Effect of Vitamin E supplementation on the enzymatic activity of selected markers in Aohan fine-wool sheep testis

Yan, Leyan; Yue, Dubing; Luo, Haiwei; Jin, Xinqiao; Xu, Xu

doi:10.1016/j.anireprosci.2010.09.001

Cited by 33 publications

(19 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, activities of G6PD, LDH, ACP and ALP were assessed to further delineate the protective role of 6‐GRF in CBZ‐induced toxicity in the present study. The involvement of these marker enzymes in the energy metabolism and stabilisation of the testes is central to spermatogenesis and sperm maturation (Yan, Yue, Luo, Jin, & Xu, ). Testicular G6PD activity in the pentose phosphate pathway furnishes reducing equivalent nicotinamide adenine dinucleotide phosphate (NADPH) for the hydroxylation of steroids necessary for spermatogenesis (Abd El Tawab, Shahin, & AbdelMohsen, ).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

6-Gingerol-rich fraction prevents disruption of histomorphometry and marker enzymes of testicular function in carbendazim-treated rats

et al. 2017

View full text Add to dashboard Cite

Previous investigations demonstrated that 6-gingerol-rich fraction (6-GRF) prevented testicular toxicity via inhibition of oxidative stress and endocrine disruption in CBZ-treated rats. The influence of 6-GRF on alterations in histomorphometry and marker enzymes of testicular function in CBZ-treated rats which hitherto has not been reported was investigated in this study. The animals were orally administered either CBZ (50 mg/kg) alone or in combination with 6-GRF (50, 100 and 200 mg/kg) for 14 consecutive days. Histomorphormetric analysis demonstrated that 6-GRF significantly prevented CBZ-mediated increase in the organo-somatic index of the testes and seminiferous tubular diameter as well as the reduction in epithelium height and tubular length of testes in the rats. Similarly, 6-GRF ameliorated CBZ-induced disruption in the epithelium height as well as in the proportion of tubule and interstitium of the epididymis the treated rats. Furthermore, 6-GRF prevented CBZ-mediated increase in testicular acid phosphatase activity and the decrease in testicular alkaline phosphatase, aminotransferases, glucose-6-phosphate dehydrogenase and lactate dehydrogenase activities. Moreover, 6-GRF ameliorated CBZ-induced reduction in the testicular and epididymal sperm count and sperm motility in the treated rats. Conclusively, 6-GRF enhances key functional enzymes involve in spermatogenesis and maintains histo-architecture of testes and epididymis in CBZ-treated rats.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Alkaline or acid phosphatase is a biomarker for primordial germ cells (Yan et al., ). The disruption in their testicular activities suggests modification of their roles in the phosphorylative pathway of testicular re‐utilisation of glucose in germ cells following CBZ exposure.…”

Section: Discussionmentioning

confidence: 99%

6-Gingerol-rich fraction prevents disruption of histomorphometry and marker enzymes of testicular function in carbendazim-treated rats

et al. 2017

View full text Add to dashboard Cite

show abstract

“…The susceptibility of spermatozoa to oxidative damage was attributed to the high concentration of unsaturated fatty acids in membrane phospholipids, the limited antioxidant capacity of spermatozoa, as well as the ability of spermatozoa to generate ROS [44]. Because spermatogenic cells are located behind the tight junction of Sertoli cells in the convoluted tubules of the testis, it is difficult for them to obtain nutrition from the testicular interstitium, and glycolysis is the dominating energy metabolism pathway in the testis [46]. Because spermatogenic cells are located behind the tight junction of Sertoli cells in the convoluted tubules of the testis, it is difficult for them to obtain nutrition from the testicular interstitium, and glycolysis is the dominating energy metabolism pathway in the testis [46].…”

Section: Discussionmentioning

confidence: 99%

Effect of Nigella sativa oil on aluminum chloride-induced testicular damage in male albino rats

Hussein

El-Ghait

Ahmed

2014

The Egyptian Journal of Histology

View full text Add to dashboard Cite

“…Lambs were assigned on the basis of body weight (BW) to one of five dietary treatments being a control diet without added vit E (CG) and four additional diets (VG) containing 20, 100, 200, and 2000 IU d -1 lamb -1 of vit E (α-tocopheryl acetate), respectively. These dose levels were 0, 1, 5, 10, and 100 times that of the NRC (1985) feeding standard, which was chosen according to our previous studies Yan et al, 2010;Ge et al, 2011;Liu et al, 2012).…”

Section: Experiments Design and Dietary Treatmentsmentioning

confidence: 99%

Effect of vitamin E supplementation on growth performance, carcass characteristics and intramuscular fatty acid composition of Longissimus dorsi muscle in Tan sheep

Zhao

Luo

Zhang

et al. 2013

Chilean J. Agric. Res.

Self Cite

View full text Add to dashboard Cite

The beneficial effects on meat quality of adding vitamin E to diets have been extensively studied in cattle and lamb. However, how supplemental vit E affects the performance and meat quality of ʽTanʼ sheep has not been reported. Thirtyfive male lambs of ʽTanʼ sheep (20-30 d after weaning) with similar body weight were randomly divided into five groups of seven each to receive a basal diet plus five levels of vit E supplementation: 0 (control group, CG), 20, 100, 200, and 2000 IU d -1 lamb -1 . The results showed: 1) no differences were observed in animal growth performance between CG and vit E treated groups (VG) (P > 0.05); 2) vit E supplementation levels over 200 IU d -1 lamb -1 dramatically suppressed subcutaneous fat deposition and similarly that above 100 IU d -1 lamb -1 considerably reduced drip loss and pH 24 h of Longissimus dorsi (LD) muscle in VG lambs compared to those of CG (P < 0.01), but with no significant effect on other carcass characteristics (P > 0.05); 3) although vit E supplementation generally did not affect the fatty acid composition of intramuscular lipids in LD muscle, the percentage of n-6 polyunsaturated fatty acids (PUFA) and the ratio of n-6/n-3 PUFA were significantly enhanced (P < 0.05) and an increasing tendency (P < 0.1) for both total PUFA proportion and the ratio of PUFA/saturated fatty acids (SFA) was also observed in ʽTanʼ sheep lambs treated with vit E. In conclusion, vit E supplementation of male ʽTanʼ sheep lambs did not influence growth performance, significantly reduced subcutaneous fat deposition, drip loss, pH 24 h and tended to improve fatty acid profile of LD muscle.

show abstract

Effect of Vitamin E supplementation on the enzymatic activity of selected markers in Aohan fine-wool sheep testis

Cited by 33 publications

References 30 publications

6-Gingerol-rich fraction prevents disruption of histomorphometry and marker enzymes of testicular function in carbendazim-treated rats

6-Gingerol-rich fraction prevents disruption of histomorphometry and marker enzymes of testicular function in carbendazim-treated rats

Effect of Nigella sativa oil on aluminum chloride-induced testicular damage in male albino rats

Effect of vitamin E supplementation on growth performance, carcass characteristics and intramuscular fatty acid composition of Longissimus dorsi muscle in Tan sheep

Contact Info

Product

Resources

About