Effect of voluntary running exercise on hypertriacylglycerolemic effect of sucrose in relation to its feeding timing in rats.

Abstract

SummaryThe effect of voluntary wheel-running to modulate sucrose induced hypertriacylglycerolemia was investigated on both sedentary and exercised rats in relation to the timing of sucrose feeding. The exercised group was allowed voluntary wheel-running between 21.00-08.00. Rats of both groups were daily meal-fed a 35% sucrose diet at 20.00-21.00 and a basal diet at 08.00-09.00, or inversely meal fed the two diets at the reversed time for 7 weeks each. At the end of the feeding period, plasma or serum triacylglycerol (TG) levels of exercised rats, as compared to sedentary rats, showed smaller diurnal changes regardless of the timing of sucrose feeding. Hepatic-intestinal TG secretion rates measured during both resting and physically active periods were lower in the exercised rats than in the sedentary control rats, whereas the cardiac and adipose tissue lipoprotein lipase activity of the two groups was not significantly different. These results suggest that voluntary wheel-running exercise may modulate the hypertriacylglycerolemic effect of sucrose in rats regardless of the timing of sucrose feeding, with decreased TG secretion. Key Words voluntary wheel-running, timing of sucrose feeding, plasma and serum TG, TG secretion, lipoprotein lipase, rat It is well known that exercise is useful to lower increased plasma TG con centrations, Sucrose feeding, on the other hand, is believed to elevate plasma TG levels. Hebert et al. (1) and Zavaroni et al. (2) have reported that this hyper triacylglycerolemic effect of sucrose was effectively inhibited by voluntary wheel running in rats when ad libitum-fed on a 63% (w/w) sucrose diet for 10 weeks or a 66% (as percent age of total calories) sucrose diet for 10days. However, using a feeding system which controls the time of meal feeding and voluntary wheel running, our recent laboratory tests have demonstrated that the sucrose feeding related to physical activity influences the plasma TG levels in rats (3). Therefore, it

Salivary 8-OHdG Induction by Physical Exercise Training Under Food Restriction

“…Each wheel revolution was registered by a magnetic switch, which was connected to a counter. The number of revolution was recorded daily [11, 12]. The EXA and CTL mice were fed ad libitum for an hour twice a day, thus the EXA mice showed more food consumption than the CTL mice.…”