Effect of Wavefront Optimized LASIK on Higher Order Aberrations in Myopic patients

Khan, Muhammad Saim; Humayun, Sadia; Fawad, Aisha; Ishaq, Mazhar; Arzoo, Sabahat; Mashhadi, Fawad

doi:10.12669/pjms.315.7683

Cited by 11 publications

(7 citation statements)

References 19 publications

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“…Studies show that myopic excimer corneal ablations cause postoperative HOAs [26,[43][44][45], and these increase with greater myopic correction [43,44,46].…”

Section: Complicationsmentioning

confidence: 99%

Refractive, visual, and subjective quality of vision outcomes for very high myopia LASIK from − 10.00 to − 13.50 diopters

Kam

Gauvin

Adiguzel³

et al. 2020

BMC Ophthalmol

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Background: To evaluate laser-assisted in situ keratomileusis (LASIK) outcomes, subjective quality of vision (QoV) and patient satisfaction in eyes with very high myopia (VHM) above − 10.00 diopters (D). Methods: Consecutive myopic and myopic-astigmatism eyes with spherical equivalent (SEQ) ranging between − 10.00 to − 13.50 D underwent LASIK with the WaveLight® Allegretto Wave® Eye-Q 400 Hz excimer laser. Treatment accuracy, efficacy, safety, stability, cylinder vectors, and higher-order aberrations were evaluated, together with subjective QoV and night vision disturbances (NVDs). Results: 114 eyes had a preoperative SEQ of − 11.02 ± 0.81 D, with a median follow-up of 24 months. A total of 72, 84, and 94% of eyes were within ± 0.50, ± 0.75 and ± 1.00 D of intended SEQ (R 2 = 0.71). The efficacy index was 0.93 ± 0.20, with 51 and 81% of eyes achieving 20/20 and 20/25. The astigmatism correction index was 0.95 ± 0.33. The safety index was 1.05 ± 0.12. The average myopic regression was − 0.51 ± 0.38 D. Preoperative QoV scores improved significantly postoperatively (7.5 ± 0.8 vs. 9.1 ± 0.7; P < 0.001), with less NVDs (P < 0.001). Total, spherical and coma root mean square (RMS) postoperative ocular higher-order aberrations were 1.07 ± 0.34, 0.67 ± 0.25, and 0.70 ± 0.40 μm. Conclusions: Very high myopia LASIK between − 10.00 to − 13.50 D is safe and results in good visual outcomes, with high patient satisfaction and a significant improvement in patient-reported QoV after surgery. Appropriately selected patients within this very high myopia group can be included as LASIK candidates.

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“…Studies show that myopic excimer corneal ablations cause postoperative HOAs [26,[43][44][45], and these increase with greater myopic correction [43,44,46].…”

Section: Complicationsmentioning

confidence: 99%

Refractive, visual, and subjective quality of vision outcomes for very high myopia LASIK from − 10.00 to − 13.50 diopters

Kam

Gauvin

Adiguzel³

et al. 2020

BMC Ophthalmol

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“…[27][28][29][30] Several studies have reported that a large part of patients experienced night vision symptoms when they had undergone with laser in situ keratomileusis (LASIK) or CRT. 9,10,15,31 Different authors found increasing higher-order aberrations and reducing low-contrast best-corrected Vision Quality of Life after LASIK and Overnight CL wear 4 visual acuity, [32][33][34][35][36][37][38][39][40] however it should be noted that in many patients the vision-related quality of life shown to be good. 12,15 These seemingly contradictory trends point to the fact that other factors than visual performance have an important role in patient satisfaction after refractive surgery or overnight CL wear.…”

Section: Introductionmentioning

confidence: 99%

Vision-Specific Quality of Life: Laser-Assisted in situ Keratomileusis Versus Overnight Contact Lens Wear

González-Pérez

García

Villa-Collar

2019

Eye &Amp; Contact Lens: Science &Amp; Clinical Practice

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Myopic subjects analyzed in this study reported better vision-related quality of life when they were corrected with continuous wear silicone-hydrogel lenses. The average score reached by CRT was similar to emmetropes, which showed the main disadvantage in worry subscale. The patients who underwent LASIK had the lowest valuation, highlighting the decreases in scores of diurnal fluctuations, glare, and especially in expectations and worry subscales, due to the first and second subscales, but especially to the false expectations created about treatment.

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“…HOAs can have a great influence on visual quality (15), and hence third order aberrations (S3-S6) and total highorder aberrations (Sh) were measured. Khan et al (16) reported that among Zernike coefficients, coma, spherical and HOAs significantly increased 1.86-, 2.44-, and 1.56-fold, respectively, at 1 month after FS-LASIK, suggesting obvious spherical aberration. Wang et al (10) reported that HOAs on the whole and anterior corneal surfaces increased significantly at 1 month after surgery, and the spherical aberration on the whole corneal and anterior corneal surfaces were significantly increased at 1 and 3 months postoperatively, along with the vertical coma on the whole and anterior corneal surfaces at 1 and 3 months.…”

Section: Discussionmentioning

confidence: 99%

High-order aberration changes after femtosecond LASIK surgery in patients with high myopia

Feng¹,

Du²,

Yang³

et al. 2021

Ann Palliat Med

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Background: To investigate the relationship between high-order aberration (HOA) changes and RCST/CT (residual corneal stroma thickness/corneal thickness) after femtosecond LASIK surgery.Methods: A total of 65 eyes from 39 patients with high myopia, who had femtosecond (FS) laser-assisted in situ keratomileusis (LASIK) surgery performed in our hospital, were included in this study. HOA and central corneal thickness were measured preoperatively and at 1 week, 1 month, and 3 months after FS-LASIK by Sirius Scheimpflug-Placido topography. Residual corneal stroma thickness (RCST) and ablation depth were measured during surgery. Results: Horizontal coma (Z 3 1 ), spherical aberration (Z 4 0 ), second horizontal coma (Z 5 1 ), second horizontal trefoil (Z 5 3 ), pentafoil (Z 5 5 ), second spherical aberration (Z 6 0 ), and total HOAs were significantly increased at 1 week, 1 month, and 3 months after surgery compared with the preoperative values (P<0.05), but no significant differences were found in horizontal trefoil (Z 3 3 ; P>0.05). Furthermore, Z 3 1 , Z 4 0 , and HOAs were significantly increased at 3 months post-surgery compared with the values at 1 week post-operation (P<0.05).Positive correlations were found between ablation depth and Z 6 0 at 1 week and 1 month after surgery (r=0.291 and 0.337, respectively; P<0.05). Ablation depth was positively correlated with Z 4 0 and Z 6 0 at 3 months after surgery (r=0.439 and 0.336, respectively; P<0.05). The RCST/CT was negatively correlated with Z 4 0 , Z 6 0 , and HOAs at 3 months after surgery (r=−0.322, −0.412, and −0.321, respectively; P<0.05). There were no significant correlations between Zernike coefficients in terms of high-order aberration, HOAs, and RCST/ CT at 1 week and 1 month post-surgery.Conclusions: Corneal HOAs in high myopia patients increased significantly after FS-LASIK surgery, and this was mainly observed as increases in coma and spherical aberration. The greater the ablation depth, the larger the influence on spherical aberrations. The greater the RCST/CT, the smaller the influence of HOAs on the cornea.

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Effect of Wavefront Optimized LASIK on Higher Order Aberrations in Myopic patients

Cited by 11 publications

References 19 publications

Refractive, visual, and subjective quality of vision outcomes for very high myopia LASIK from − 10.00 to − 13.50 diopters

Refractive, visual, and subjective quality of vision outcomes for very high myopia LASIK from − 10.00 to − 13.50 diopters

Vision-Specific Quality of Life: Laser-Assisted in situ Keratomileusis Versus Overnight Contact Lens Wear

High-order aberration changes after femtosecond LASIK surgery in patients with high myopia

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