Effect on the rat uterus of the venom from the scorpion Leiurus quinquestriatus

Osman, O.H.; Ismail, M.; El-Asmar, M.F.; Ibrahim, S.

doi:10.1016/0041-0101(72)90059-1

Cited by 32 publications

(13 citation statements)

References 4 publications

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“…Like other OldWorld species, their venoms contain numerous neurotoxins that affect the activity of many ion channels of excitable cells. Such actions may be responsible for the contractions of non-pregnant female uteri (18,19,21,22) induced by the venom of different Old-World scorpion species. Scorpion venom has increased estradiol serum levels (21), and prostaglandin F2 alpha uterine biosynthesis (1) may also increase uterine contraction via its bradykinin-potentiating fraction.…”

Section: Resultsmentioning

confidence: 99%

Scorpion envenomation symptoms in pregnant women

Ben-Nasr¹,

Hammami²,

Z³

et al. 2007

J. Venom. Anim. Toxins incl. Trop. Dis

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Scorpion envenomation is common in many countries; however, its effects on pregnancy are still unclear. In the present paper, we described the effects of scorpion envenomation on pregnant patients. A retrospective study was carried out considering the clinical and laboratory exams of patients admitted to the emergency room of Habib Bourguiba Hospital, Sfax, Tunisia, from 1990 to 2004. Variability of these clinical and laboratory profiles according to maternal age, gestational age and number of previous parities was also discussed. Among 167 scorpion-envenomed women, age ranged from 17 to 42 years, 7.18% were pregnant. These presented symptoms similar to those of non-pregnant women envenomed by scorpions. Two pregnant patients developed intense pelvic pain and one manifested vaginal bleeding. Although the studied parameters showed non-significant differences, we could conclude that scorpion envenomation may lead to abnormal uterine contraction probably causing preterm delivery. Maternal disturbances induced by scorpion envenomation may influence the fetus development. The effects were more severe in the second trimester of pregnancy.KEY WORDS: pregnant women, scorpion envenomations, signs and symptoms, laboratory data.

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Section: Resultsmentioning

confidence: 99%

Scorpion envenomation symptoms in pregnant women

Ben-Nasr¹,

Hammami²,

Z³

et al. 2007

J. Venom. Anim. Toxins incl. Trop. Dis

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“…Ratlarda yapılan bir çalışmada Leiurus quinquestriatus türü akrep sokmalarında birçok olguda ilk trimesterde düşüklere neden olduğu gösterilmiştir 6 . Leiurus quinquestriatus venomunun rat uterusunda kontraksiyon sıklığını ve şiddetini belirgin olarak arttırdığı gösterilmiştir.…”

Section: Discussionunclassified

Scorpion sting in pregnancy

Gökay¹,

Çelik²,

Yılmaz³

et al. 2015

Turk J Ped Em Int Care Med

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Scorpion Sting in Pregnancy ÖZETAkrep sokması sonrasında ha f yerel bulgulardan yaşamı tehdit edebilecek ağır sistemik bulgulara kadar değişebilen klinik seyir gözlenebilir. Bu olgu sunumumuzda, literatürde kısıtlı bilgiye sahip olduğumuz ve çocuk acillerde nadir karşılaştığımız akrep sokması sonrası çocuk acile başvuran bir gebede ve fetüste akrep toksininin etkilerini tartışmayı amaçladık. Olgumuz 17 yaşında 35 gestasyonel hafta+1 günlük gebe akrep sokması sonrasında acile başvurdu. Yerel bulgu dışında belirti ve bulgusu olmayan hasta, herhangi bir tedavi verilmeden yakın izlendi. Hastada ve fetusta yirmi dört saatte herhangi bir bulgu gelişmemesi üzerine önerilerle taburcu edildi. Sonuç olarak, akrep sokması farklı klinik bulgularla acile başvurabilir. Tedaviyi düzenlerken akrep antiserumunun yan etkileri de düşünülerek hareket edilmeli, hastanın kliniğine göre karar verilmelidir. Gebelikte akrep sokmasıyla ilgili sınır-lı bilgiye sahip olduğumuz için gebe hasta grubunda hem anne, hem fetus göz önüne alınarak tedavi seçenekleri değer-lendirilmelidir CAYD 2015;2(1):41-44. Anah tar Ke li me ler: Gebelik, Akrep sokması, Fetus Y R A M M U S Scorpion stings are rarely encountered in the pediatric emergency department. Post-sting clinical manifestations range from mild localized skin erythema to life-threatening systemic reaction. We present a case of scorpion sting in a 17 years old, 35 weeks +1 day pregnant female evaluated in our emergency department. The patient presented to our emergency department with localized skin irritation at the site of the sting. No symptoms of systemic involvement were noted in the ED and the patient was admitted to the hospital for further evaluation. No anti-venom was administered during hospitalization and the patient was discharged home in good condition and no adverse e ects were noted on the unborn fetus. Conclusion: In pregnant patients with scorpion sting and localized skin irritation following scorpion sting anti-venom may be safely withheld. Decisions regarding the use of anti-venom in pregnant women should be carefully considered given the limited information on the safety pro le of anti-venom in these patients and e ect on the unborn fetus CAYD 2015;2 (1)

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“…In literature there is a few anecdotal observations of yellow scorpion stings resulting in early abortions in pregnant women [10]. There is a case report in literature that the patient have fetal death following a yellow scorpion sting [11].…”

Section: Discussionmentioning

confidence: 99%

Scorpion sting during pregnancy: A case report accompanied by literature

Kamalak¹,

Köşüş²

2013

CMJ

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Envenomation is an unusual event in developed countries. Rural population who lives in arid climate is incur this danger. Scorpion sting is one of the envenomation. It is a major public health problem in many underdeveloped tropical countries. In Turkey, epidemiological studies have shown that most scorpion stings affect females. The highest incidence of scorpion stings was recorded for the warmest months of the year since scorpions become more active in the warm season. Diagnosis is obvious from the history. Also pain, erythema, induration, and wheal may be present at the sting point. In pregnancy envenoming is more dangerous but scorpion envenoming is less studied during gestation; however, it may induce various biological disturbances in maternal organism and on their fetuses. In this article the aim is bring on a subject for discussion on a case report. Keywords: Scorpion envenomation, pregnancy ÖzetEnvenomizasyon yani yılan veya akrep gibi zehirli sürüngen ve haşerelerle sokularak zehirlenme kurak iklimin hakim olduğu kırsal bölge halkı için ciddi bir risktir. Türkiye'de yapılan epidemiyolojik çalışmalar bu durumdan özellikle dişilerin etkilendiğine işaret etmektedir. Tanı ise anamneze bağlı olup ağrı, eritem, endurasyon ve belki haşerenin sokma noktasının görülmesine bağlıdır. Gebelikte envenomizasyon ise çok daha riskli olmasına rağmen üzerinde oldukça az çalışılmış bir konudur oysa ki hem maternal ve hem de fetal riskler söz konusudur. Biz bu yazımızda bir vakamızı literatür eşliğinde tartışmak istedik.

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Effect on the rat uterus of the venom from the scorpion Leiurus quinquestriatus

Cited by 32 publications

References 4 publications

Scorpion envenomation symptoms in pregnant women

Scorpion envenomation symptoms in pregnant women

Scorpion sting in pregnancy

Scorpion sting during pregnancy: A case report accompanied by literature

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