Effective application of ET-Kyoto solution for clinical lung transplantation

Preservation, sterilization and de-epithelialization of human amniotic membrane for use in ocular surface reconstruction

“…Chen et al [162] has reported that trehalose-containing organ preservation has been used for lung transplantation. Matsuo et al [163] reported the effectiveness and safety of trehalose solution as an eye drop for the treatment of moderate to severe dry-eye syndrome.…”

Lyophilized Aspirin with Trehalose May Decrease the Incidence of Gastric Injuries in Healthy Dogs

“…It is widely used as a food ingredient and in the cosmetics industry [10,41]. Recently, it has undergone several clinical trials on organ preservation during transplantation [4], inhibition of xenosis during dental treatment [22], therapy of dry eye syndrome [19], and adhesion prevention after abdominal surgery [12]. Recent studies found several novel anti-inflammatory and protective functions of trehalose.…”

Phosphoenolpyruvic Acid, an Intermediate of Glycolysis, Attenuates Cellular Injury Induced by Hydrogen Peroxide and 2-Deoxy-D-glucose in the Porcine Proximal Kidney Tubular Cell Line, LLC-PK1

“…These preservation solutions seem to achieve better results than other preservation solutions. 23,24) In addition, carbohydrates such as glucose and trehalose are added to preservation solutions to reduce energy depletion from organs/cells during preservation. PEP may be an attractive bifunctional carbohydrate with the potential to act as both energy supplier and antioxidant.…”