Intercultural communication in multinational organizations from the perspective of open innovation is the critical role of in today's interconnected world. Cultural diversity has become a defining characteristic of multinational corporations, shaping their organizational dynamics and competitive strategies. Open innovation, characterized by collaborative knowledge exchange across borders, has emerged as a powerful approach for driving creativity and breakthrough innovations. This chapter explores how successful intercultural communication practices can enhance open innovation initiatives within multinational organizations, leading to accelerated product development, improved market responsiveness, and expanded global networks. Drawing on existing research and real-world case studies, this chapter provides valuable insights into the transformative impact of intercultural communication on fostering creativity, leveraging diverse perspectives, and driving innovation-driven growth in the context of multinational organizations' open innovation endeavours.