Effectiveness for pain after laparoscopic cholecystectomy of 0.5% bupivacaine-soaked Tabotamp® placed in the gallbladder bed: a prospective, randomized, clinical trial

Abstract

Bupivacaine, either infiltrated in trocars' wounds or kept soaked in a regenerated oxidized cellulose sheet positioned in the gallbladder bed, although safe and not economically demanding, can increase postoperative comfort.

Comparison of Pain Relief By Placing Regenerated Oxidized Cellulose Sheet Soaked in Bupivacaine And Port Site Infiltration With Bupivacaine Post-Laparoscopic Cholecystectomy: A Randomized Control Trial

“…This was at odds with results of other studies by Chundrigar T et al [8] -12%, Feroci F et al [3] -44% and Verma G R et al [4] -14%. It is difficult to attribute any particular cause to the absence of shoulder pain in this study.…”

“…If necessary drain was inserted through lateral trocar and positioned in sub-hepatic region. In Group A after removal of GB, 0.5% bupivacaine soaked ROC was placed in GB bed [3,4] (Fig. 1).…”

“…Pain management has not been standardized at mass medical centers in India and abroad and this is reflected in the number of different pain studies after LC available in literature. Till day, many different methods have been used with conflicting rates of success to diminish the intensity of PO pain after LC [1][2][3][4][5][6][7][8][9]. They include low pressure pneumoperitoneum, gasless technique of LC, use of warm carbon dioxide, peritoneal wash with saline solution, strict surgical technique, perfect hemostasis, trocar site infiltration of anaesthetic drugs, instillation ofsubdiaphragmatic region with anaesthetic/analgesic drugs, or use of nonsteriodal anti-inflammatory drugs or dexamethasone.…”

“…They include low pressure pneumoperitoneum, gasless technique of LC, use of warm carbon dioxide, peritoneal wash with saline solution, strict surgical technique, perfect hemostasis, trocar site infiltration of anaesthetic drugs, instillation ofsubdiaphragmatic region with anaesthetic/analgesic drugs, or use of nonsteriodal anti-inflammatory drugs or dexamethasone. [1][2][3][4][5][6][7][8][9] To gain a major insight into the effectiveness of intraperitoneal use of 0.5% bupivacaine soaked sheet of regenerated oxidized cellulose and port site infiltration of bupivacaine in PO pain relief after laparoscopic cholecystectomy, the present study was carried out in the Department of General Surgery, A. J. Institute of Medical Sciences.…”

Control Del Dolor en La Colecistectomía Laparoscópica Mediante La Aplicación De Bupivacaína en El Lecho De La Vesícula. Hospital Eugenio Espejo-Quito, 2012.

“…Así mismo un metaanálisis [20] donde fue válido la aplicación intraperitoneal de anestésico local. Dos en un estudio prospectivo, aleatorio doble ciego se encuentra efectividad en el uso de la bupivacaína para el control del dolor [21] estudian la bupivacaína empapada en una lámina de celulosa además de la infiltración en las incisiones de los trocares donde el resultado es la disminución del dolor postoperatorio [22] encuentran diferencia estadística en…”