Effectiveness of a vaccination program against mumps in Ukraine

Hrynash, Y.; Nadraga, O.B.; Dasho, M. B.

doi:10.1007/s10096-008-0575-6

Cited by 12 publications

(8 citation statements)

References 14 publications

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“…Seasonal variation in the incidence of mumps has been reported in different areas. Of these, a seasonal pattern has been detected in the USA, with significant peaks in April [4] ; more cases occur in winter and spring than in summer and autumn in the Ukraine [5] ; frequency is higher in winter and spring with epidemic peaks in Jordan [6] ; and incidence is highest in the spring, next highest in autumn, and lowest in summer in Taiwan [7]. The seasonality of the disease suggests that weather factors might play an important role in its incidence and indicates the possibility of multiple functional pathways.…”

Section: Introductionmentioning

confidence: 99%

Effect of weather variability on the incidence of mumps in children: a time-series analysis

Onozuka

Hashizume

2011

Epidemiol. Infect.

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The increasing international interest in the potential health effects of climate change has emphasized the importance of investigations into the relationship between weather variability and infectious diseases. However, few studies have examined the impact of weather variability on mumps in children, despite the fact that children are considered particularly vulnerable to climate change. We acquired data about cases of mumps in children aged <15 years and weather variability in Fukuoka, Japan from 2000 to 2008, and then used time-series analyses to assess how weather variability affected mumps cases, adjusting for seasonal variations, inter-annual variations, and temporal variations of two large epidemics in 2001 and 2004-2005. The weekly number of mumps cases increased by 7·5% (95% CI 4·0-11·1) for every 1°C increase in average temperature and by 1·4% (95% CI 0·5-2·4) for every 1% increase in relative humidity. The percentage increase was greatest in the 0-4 years age group and tended to decrease with increasing age. The number of mumps cases in children increased significantly with increased average temperature and relative humidity.

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Section: Introductionmentioning

confidence: 99%

Effect of weather variability on the incidence of mumps in children: a time-series analysis

Onozuka

Hashizume

2011

Epidemiol. Infect.

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“…[ 4 ] In Ukraine, most cases of mumps occur in winter and spring. [ 36 ] Our results showed a seasonal pattern of mumps infection with a peak occurrence in the spring and summer months. Our findings were similar to those of previous studies in China, [ 37 , 38 ] but differed from those in Jordan.…”

Section: Discussionmentioning

confidence: 66%

The incidence of mumps in Taiwan and its association with the meteorological parameters

Lin

Peng

et al. 2021

Medicine

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Mumps is an acute and common childhood disease caused by paramyxovirus. It has been reported that the occurrence of mumps is influenced by seasonality. However, the role of meteorological variables in the incidence of mumps remains unclear. The purpose of this study was to explore the relationship between meteorological factors and the incidence of mumps infection. Poisson regression analysis was used to study the relationship between weather variability and the incidence of mumps in Taiwan. Between 2012 and 2018, 5459 cases of mumps cases were reported to the Centers for Disease Control, Taiwan (Taiwan CDC). The occurrence of mumps virus infections revealed significant seasonality in the spring and summer seasons in Taiwan. The incidence of mumps virus infections began to increase at temperatures of 15°C and started to decline if the temperature was higher than 29°C ( r 2 = 0.387, P = .008). Similarly, the number of mumps cases began to increase at a relative humidity of 65% to 69% ( r 2 = 0.838, P < .029). The number of mumps cases was positively associated with temperature and relative humidity during the period preceding the infection. This study showed that the occurrence of mumps is significantly associated with increasing temperature and relative humidity in Taiwan. Therefore, these factors could be regarded as early warning signals and indicate the need to strengthen the intervention and prevention of mumps.

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“…While the parotid glands are the most commonly affected organ, mumps may also affect several other organs, such as the testes, central nervous system, pancreas, and articulars [11]. The incidence of mumps diminished dramatically in the past 25 years after the introduction of the measles, mumps, and rubella (MMR) vaccine in the world [12].…”

Section: Discussionmentioning

confidence: 99%

Long-term efficacy and safety of interferon-alpha-2B in patients with mumps orchitis

et al. 2010

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The aim of this study was to determine long-term efficacy and safety subcutaneous injection of interferon-alpha-2B in patients with mumps orchitis in terms of testicular volume and other testicular functions. Mumps orchitis was evaluated in 37 patients. Patients were hospitalized and administered 1 × 3,000,000 IU subcutaneous injection of interferon-alpha-2B daily for 7 days. The testicular volumes of all the patients were measured by ultrasonography in the 18th month following treatment termination. The testes volumes were evaluated by descriptive statistics as percentages. Patients were divided into three groups according to testes volumes and differences between the involved and non-involved testicles. Group I included patients with normal testes volume (> 12 ml) and a difference between testes of less than 2 ml or 20%; Group II (atrophic groups) included patients with testes volume of less than 12 ml; and Group III (hypotrophic groups) included patients with testes volume of greater than 12 ml and a difference between testes of more than 2 ml or 20%. Groups were compared in terms of results of semen analysis and serum follicle stimulating hormone (FSH) and luteinizing hormone (LH) levels. Patients' ages ranged between 17 and 41 years (mean: 28.3 years). A total of nine atrophy cases were identified. Sixteen patients were determined to have hypotrophic testes with a difference of 2-10 ml or 20% between the involved and non-involved testicles, despite the absence of testicular atrophy. A comparison of groups revealed that sperm density, total sperm count, total motile sperm count, and motility percentage were significantly higher in Group I than in the other groups, while serum FSH and LH levels were lower in Group I than in the other groups. Although the use of interferon-alpha-2B appears to prevent testicular atrophy and protect testicular function, it leads to a considerable difference in the volume between testicles and a significant loss of testicular function. As a result, further studies are required in order to investigate the efficacy of the drug.

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Effectiveness of a vaccination program against mumps in Ukraine

Cited by 12 publications

References 14 publications

Effect of weather variability on the incidence of mumps in children: a time-series analysis

Effect of weather variability on the incidence of mumps in children: a time-series analysis

The incidence of mumps in Taiwan and its association with the meteorological parameters

Long-term efficacy and safety of interferon-alpha-2B in patients with mumps orchitis

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