Effectiveness of antithrombotic prophylaxis in paediatric cardiosurgical patients

Abstract

<p><strong>Aim.</strong> To evaluate the effectiveness of prevention measures for thrombotic catheter-associated events in the perioperative management of patients undergoing cardiac surgery.</p><p><strong>Methods.</strong> A total of 433 paediatric and neonatal patients were included in the study during the period from January to December 2018. All patients received antithrombotic prophylaxis via systemic heparin administration.</p><p><strong>Results.</strong> Thirty-six patients displayed signs of thrombosis during the postoperative period (8.31%): 28 patients had venous thrombosis, while 6 had the Blalock-Taussig shunt thrombosis, and 2 had arterial thrombosis. The mortality rate was higher in the group with registered thrombosis than in the group without thrombosis (p = 0.01).</p><p><strong>Conclusion.</strong> The dosage regimen for children and neonatal patients should be according to age-associated antithrombotic drug standards. It requires an integral approach for evaluating the effectiveness of preventive and therapeutic measures.</p><p>Received 25 August 2020. Revised 18 December 2020. Accepted 22 December 2020.</p><p><strong>Funding:</strong> The study did not have sponsorship.</p><p><strong>Conflict of interest:</strong> Author declares no conflict of interest.</p>