Child disability is a major concern for any nation. Childhood comorbidity is not only a challenge for parents but also a big concern for pediatricians. The motor disorder of cerebral palsy (CP) is often accompanied by disturbances of sensation, perception, cognition and has multifactorial etiology. Vata is dominant Dosha which plays a major role in childhood disabilities, so the treatment plan should be Vata Shamana like Phakka Roga Chikitsa, and Shiromarmabhighata can be used. The use of Rasayanas with Medhya drugs (intellect promoting) characteristics will enhance the child's mental and physical development. This will go a long way toward curing and preventing impairments. To search and reassess the effects of different CP therapy techniques in Ayurveda. Analysis of published clinical data in a systematic manner to determine the efficacy and safety of Vatavyadhi versus Ayurvedic therapy protocols for CP. The study examined case reports, non-randomized controlled trials (RCTs), and RCTs on the treatment of CP in Ayurveda. They were located using directories of open-access publications as well as databases for Ayurvedic research and medical journals, including MEDLINE, SCOPUS, and Web of Science. Hand-searching was conducted with pre-established search criteria. Search results were only returned for articles up to April 2021. The selection of studies was based on CP symptomatology. The study ID, design, sample size, duration, interventions, results, and outcomes were used to document and retrieve the data. Using the tools at hand, the quality and bias risk were assessed. We did not try quantitative synthesis because we were only interested in systematic review. 20 of the 44 screened records met the predetermined criterion. Two research on Nasya (medicine administered through the nose), 8 studies on Udavartana (application of dry powder to the skin), 9 studies on Shasthi Shali Pinda SwedaSwedana (hot fomentation with rice cooked in milk) and 16 studies concentrating on Basti (therapeutic enema) as the main management strategy is among the most frequently used therapies. The outcomes were divided into Bhaya chikitsa (external procedures), Shamana (palliative medicines), and Shodhana (purification medicines). Overall investigations reveal a significant improvement in the gradation index-measured subjective characteristics. Better alleviation was seen when panchakarma therapy was paired with oral medication. The study's findings led to a significant improvement in spasticity and muscle power and helped to maintain a better quality of life, which is widely appreciated.