Effects and formulation of silver nanoscaffolds on cytotoxicity dependent ion release kinetics towards enhanced excision wound healing patterns in Wistar albino rats

Abstract

A sustained and controlled release of silver ions from AgNPs is driven by greater percentage of wound contraction with minimal cytotoxic behavioural rates and effective antibacterial activity.

RETRACTED ARTICLE: Cerium oxide nanoparticle-loaded polyvinyl alcohol nanogels delivery for wound healing care systems on surgery

“…After 6 and 12 days, wounds dressed in the Ce-nGel and Ce-nGel-Glu achieved a large closure of around 95%, in contrast to 65% wound closure of the bare wounds (Figure 8). Therefore, in vivo study of Sprague-Dawley rats confirmed the increased wound healing ability of the as-fabricated Ce-nGel-Glu (Ghobril & Grinstaff, 2015;Sethuram et al, 2019;Zhang et al, 2020).…”

Eugenol micro-emulsion reinforced with silver nanocomposite electrospun mats for wound dressing strategies

“…The conventional bilayer non-adhesive pad was obtained through Dakar Company (medical safety private emergency limited, located in Israel) and the samples were characterized. 19 The bilayer non-adhesive pad was cut into small pieces and dissolved in purified de-ionized water/ammonia solution prior to homogenization process. Centrifugation was done for 15 minutes at 8000 rpm to prepare a transparent solution.…”

“…PVA-AgNPs incorporated with CAM accelerates the wound healing potential in wistar albino rat models and found comparatively more effective than other synthetic polymer capped AgNPs which is reported in the previous study. 19 Eugenol is an antimicrobial phenolic component of cinnamon essential oil known for anti-inflammatory, antioxidant, anticarcinogenic and analgesic properties. 20,21 Eugenol is highly volatile and insoluble in water that gets affected by enzymatic and chemical degradation, and losses occur due to thermal decomposition and volatilization.…”

Fabrication and evaluation of vitamin doped Zno/AgNPs nanocomposite based wheat gluten films: a promising findings for burn wound treatment

“…Additionally, ZnO is less toxic and serves as a source of Zn, that is required by 300 catalytic enzymes that influence cell differentiation and proliferation as well as wound healing 17 . Likewise, Ag NPs have gained a new therapeutic potential to be employed in wound dressings owing to their safety, reliability, low toxicity, potency, and resistance to various bacteria 18 . The unique physicochemical properties of these NPs are suitable for enhanced encapsulation, active and passive targeted delivery, and regulated and sustained drug release 19 , 20 .…”

“…The unique physicochemical properties of these NPs are suitable for enhanced encapsulation, active and passive targeted delivery, and regulated and sustained drug release 19 , 20 . Therefore, various nano-based dressinghave been fabricated by the integration of NPs with different biocompatible polymers, like chitosan, polylactic acid (PLA), polyvinyl pyrrolidone (PVP), and polyvinyl alcohol (PVA), for efficient wound healing applications 18 , 19 , 21 .…”