Effects of Arachis hypogaea nutshell extract on lipid metabolic enzymes and obesity parameters

Moreno, Diego A.; Ilić, Nebojša; Poulev, Alexander; Raskin, Ilya

doi:10.1016/j.lfs.2005.11.012

Cited by 89 publications

(55 citation statements)

References 39 publications

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“…These pancreatic lipase inhibitory phytochemicals include mainly saponins, polyphenols, flavonoids, and caffeine [38][39][40]. The most studied natural sources of pancreatic lipase inhibitors are derived from different types of tea (e.g.…”

Section: Lipase Inhibitionmentioning

confidence: 99%

Review Article: Herbal Approach for Obesity Management

Chandrasekaran¹,

Vijayalakshmi²,

Prakash³

et al. 2012

AJPS

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Obesity, a complex interplay between environmental and genetic factors and is associated with significant morbidity and mortality. Usage of herbs for the management of obesity in the recent times is attracting attention. A web and manual based literature survey was conducted to assess the amount of information available on the herbal products for weight management. Traditional literature, PubMed, Scopus, Google scholar databases were screened up to February 2012. The search words were "obesity", "herbal medicine/products/extracts", "medicinal plants", "traditional medicine", "Ayurvedic medicine" without narrowing/limiting searching words or elements. Publications only with abstracts/full articles and books were reviewed in the search. Based on the available literature, for many of the herbal and weight loss products, there is little published information and there have been no clinical trials or the level of evidence is limited. Our literature survey also indicated that these herbal products fall under an acceptable level of evidence or with no scientific background at all, or they have a scientific rational but not to an acceptance level. Attempts were made in the review to define the features of possible herbal weight loss product. An ideal herbal anti obesity product should reduce the weight by 10% over placebo of treatment by showing an evidence of improvement of bio markers like blood pressure, lipids and glycemia without any side effects.

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Section: Lipase Inhibitionmentioning

confidence: 99%

Review Article: Herbal Approach for Obesity Management

Chandrasekaran¹,

Vijayalakshmi²,

Prakash³

et al. 2012

AJPS

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“…206 The peanut shell extract also shows inhibitory effects on human lipase, with a dose of 10 mg/mL inhibiting 92% of activity. 207 When administered as 1% of a high fat diet, PSE reduced weight gain in normal adult rats without altering food consumption. 207 …”

Section: Peanut and Peanut Shell Extract (Pse)mentioning

confidence: 99%

The role of lipid and carbohydrate digestive enzyme inhibitors in the management of obesity: a review of current and emerging therapeutic agents

Tucci¹

2010

DMSO

123

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“…This pancreatic lipase inhibitory phytochemicals include mainly, polyphenols, flavonoids, saponins and caffeine [136][137][138][139]. Many carbohydrates also possess potent PL inhibitory effects [140,141].…”

Section: Inhibitory Effect On Pancreatic Lipase Enzymementioning

confidence: 99%

Obesity: Development, Epidemiology, Factors Affecting, Quantity, Health Hazards, Management and Natural Treatment-a Review

Bollapragada

Shantaram

Kumar

2017

Int J Pharm Pharm Sci

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Due to the advancement in science, enhanced knowledge on the physiological aspects of almost all the tissues and the organs of the human body is gained. One of the most important prevalent topics needed for discussion is obesity and its effect on the metabolic changes leading to disorders in the human body such as diabetes, hypertension, cardiovascular diseases in addition to chronic diseases such as stroke, osteoarthritis, sleep apnea, some cancers, and inflammation-based pathologies. In recent years, obesity is a serious socioeconomic issue, which has become one of the major health problems all over the world, affecting people of all ages, sex, ethnicities and races. Obesity is a complex and multifactorial disease caused by the interaction of a myriad genetics, dietary, lifestyle and environmental factors and it is characterised by an excessive weight for height due to an enlarged fat deposition in the adipose tissue, which is due to a higher calorie intake than the energy expenditure. The pharmaceutical drugs are currently available to treat obesity but generally they have unpleasant side effects. Recent researches demonstrated the potential of natural products to counteract on obesity. Now the novel promising approach is the usage of dietary supplements and plant products and their bioactive compounds that could interfere on pancreatic lipase activity, food intake, lipid metabolism and adipocyte differentiation. In a similar way, hundreds of extracts are currently being isolated from plants, fungi, algae or bacteria and are screened for their potential inhibitions of activity against obesity. Natural products may have a synergistic activity that increases their bioavailability and action on multiple molecular targets.

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Effects of Arachis hypogaea nutshell extract on lipid metabolic enzymes and obesity parameters

Cited by 89 publications

References 39 publications

Review Article: Herbal Approach for Obesity Management

Review Article: Herbal Approach for Obesity Management

The role of lipid and carbohydrate digestive enzyme inhibitors in the management of obesity: a review of current and emerging therapeutic agents

Obesity: Development, Epidemiology, Factors Affecting, Quantity, Health Hazards, Management and Natural Treatment-a Review

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