Effects of cannabis use on cognitive function and clinical features of bipolar disorder

Halder, Ajay; Mukhopadhyay, Sikha; Biswas, Partha; Biswas, Abhinanda

doi:10.4103/2395-2296.189677

Cited by 5 publications

(3 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Similarly, Ringen et al (2010) observed better cognitive function in cannabis users than non-users with BD. In contrast, two studies found no association between cannabis use and cognitive function (Sagar et al 2016;Abush et al 2018), and one observed worse performance in symptomatic BD patients with comorbid CUD (Halder et al 2016).…”

Section: Overlapping Neurocognitive Substratesmentioning

confidence: 90%

Associations between cannabis use, cannabis use disorder, and mood disorders: longitudinal, genetic, and neurocognitive evidence

et al. 2021

View full text Add to dashboard Cite

show abstract

Section: Overlapping Neurocognitive Substratesmentioning

confidence: 90%

Associations between cannabis use, cannabis use disorder, and mood disorders: longitudinal, genetic, and neurocognitive evidence

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Secondly, studies differed on the mood status of the participants included. These studies mostly examined stable patients, with one study including some patients who were symptomatic (Braga et al, 2012), and one study examining only acutely symptomatic participants (Halder et al, 2016). Halder et al was also the only study to find that cannabis use was associated with worse cognition in people with BD.…”

Section: Discussionmentioning

confidence: 99%

The Relationship between Cannabis Use and Cognition in People with Bipolar Disorder: A Systematic Scoping Review

Walter

Pocuca

Young

et al. 2020

Preprint

View full text Add to dashboard Cite

Bipolar disorder (BD) and cannabis use are highly comorbid and are each associated with cognitive impairment. It is therefore important to understand the relationship between cannabis use and cognition in people with BD, as cannabis use in BD may be associated with greater cognitive impairment. We performed a scoping review to determine how much and what is currently known in this field. We systematically searched PubMed, Embase, CINAHL, Web of Science, and PsycINFO for studies on the relationship between cannabis and cognition in people with BD or relevant animal models. Six observational human studies met inclusion criteria. Two studies found cannabis use in BD was associated with better performance in some cognitive domains, while three studies found no association. One study found cannabis use in BD was associated with worse overall cognition. Overall, most identified studies suggest cannabis use is not associated with significant cognitive impairment in BD; however, the scope of knowledge in this field is limited, and more systematic studies are clearly required. Future studies should focus on longitudinal and experimental trials, as well as well-controlled observational studies with rigorous quantification of the onset, frequency, quantity, duration, and type of cannabis use.

show abstract

“…A third study examined neurocognition in four different groups, ages ranging from 18 to 45 years: healthy control (HC) adults, adults with cannabis dependence only, adults with BD only, and adults with both BD and cannabis dependence. This study reported that neurocognitive performance decreased linearly across these groups (Halder et al, 2016). A fourth study of adolescents and young adults, aged 16–35 years, found no neurocognitive differences when comparing participants with BD who used cannabis to participants with BD who did not use cannabis (Sagar et al, 2016).…”

Section: Introductionmentioning

confidence: 89%

Association of cannabis use with neurocognition in adolescents with bipolar disorder

et al. 2023

View full text Add to dashboard Cite

Background: Bipolar disorder (BD) and cannabis use are each associated with neurocognitive deficits in adolescents. However, little is known regarding the association of neurocognition with cannabis use among adolescents with BD. Therefore, we examined this topic in a sample of adolescents with BD and healthy control (HC) adolescents. Methods: Participants included 121 adolescents ( n = 32 with BD and lifetime cannabis use (BDCB+), n = 31 with BD and no lifetime cannabis use (BDCB−), n = 58 HC with no lifetime cannabis use), aged 14–20 years. Five neurocognitive subtests of the computerized CANTAB battery were assessed. Groups were compared using an analysis of covariance (ANCOVA) covarying for age, sex, and intelligence quotient. Results: The three groups differed significantly on tests of visuospatial working memory ( F = 4.41, p = 0.014, [Formula: see text]) and sustained attention ( F = 5.15, p = 0.007, [Formula: see text]). Post hoc analyses revealed working memory scores were significantly worse in BDCB+ versus HC ( p = 0.04, d = 0.59), and sustained attention was significantly worse in BDCB− versus HC ( p = 0.006, d = 0.70). Conclusion: These preliminary findings suggest that cannabis use among adolescents with BD is associated with working memory deficits. Future studies in larger samples are warranted to evaluate causation versus predisposition to cannabis use, and to evaluate duration, quantity, and potency of cannabis on neurocognition among adolescents with BD.

show abstract

Effects of cannabis use on cognitive function and clinical features of bipolar disorder

Cited by 5 publications

References 1 publication

Associations between cannabis use, cannabis use disorder, and mood disorders: longitudinal, genetic, and neurocognitive evidence

Associations between cannabis use, cannabis use disorder, and mood disorders: longitudinal, genetic, and neurocognitive evidence

The Relationship between Cannabis Use and Cognition in People with Bipolar Disorder: A Systematic Scoping Review

Association of cannabis use with neurocognition in adolescents with bipolar disorder

Contact Info

Product

Resources

About