Effects of dietary intake, appetite, and eating habits on dialysis and non-dialysis treatment days in hemodialysis patients: cross-sectional results From the HEMO study

Burrowes, Jerrilynn D.; Larive, Brett; Cockram, David B.; Dwyer, Johanna T.; Kusek, John W.; McLeroy, Sandra; Poole, Diane J.; Rocco, Michael V.

doi:10.1016/s1051-2276(03)00069-4

Cited by 139 publications

(98 citation statements)

References 15 publications

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“…The elderly patient may arrive home too fatigued to eat before retiring to bed (23). In this context, we hypothesize that a similar number of hospital-free days survived between the MCM and the hemodialysis-only subgroup may represent a much smaller difference in quality of life than would be expected from the quantitative overall survival difference.…”

Section: Discussionmentioning

confidence: 96%

Is Maximum Conservative Management an Equivalent Treatment Option to Dialysis for Elderly Patients with Significant Comorbid Disease?

Carson

Juszczak

Davenport

et al. 2009

Clinical Journal of the American Society of Nephrology

401

388

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Background and objectives: There is ongoing growth of elderly populations with ESRD in Western Europe and North America. In our center, we offer an alternative care pathway of 'maximum conservative management' (MCM) to patients who elect not to start dialysis, often because of a heavy burden of comorbid illness and advanced age. The objective of our study was to compare clinical outcomes for patients who had ESRD and chose either MCM or renal replacement therapy (RRT).Design, setting, participants, & measurements: This is an observational study of a single-center cohort in the United Kingdom that evaluating 202 elderly (>70 yr) patients who had ESRD and had chosen either MCM (n ‫؍‬ 29) or RRT (n ‫؍‬ 173). We report survival, hospitalization rates, and location of death for this cohort. Survival was measured from a standardized 'threshold' estimated GFR of 10.

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Section: Discussionmentioning

confidence: 96%

Is Maximum Conservative Management an Equivalent Treatment Option to Dialysis for Elderly Patients with Significant Comorbid Disease?

Carson

Juszczak

Davenport

et al. 2009

Clinical Journal of the American Society of Nephrology

401

388

View full text Add to dashboard Cite

show abstract

“…Many studies reported that these recommendations are far from being fully obtained; [8][9][10] moreover, chronic renal failure is associated with loss of appetite and reduced food intake, especially when toxins removal by hemodialysis is inadequate. 11 Dialysis adequacy and nutritional counseling are the first attempts to ameliorate nutritional status, and then oral nutritional supplements should be employed including energy and protein sources. 12 Actually, use of renal-specific oral supplements by hemodialysis patients with low protein intake may prevent a decline in nutritional status and quality of life without increasing the need of phosphate binders.…”

Section: Introductionmentioning

confidence: 99%

A Novel Amino Acids Oral Supplementation in Hemodialysis Patients: a Pilot Study

et al. 2011

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Background: Protein malnutrition and lowering serum albumin is frequent in hemodialysis patients. A special amino acid formulation has recently been used with favorable effects in elderly people but no data exist in renal patients. Aim: To assess the effects of this novel amino acid formulation in stable hemodialysis patients with reduced albumin levels. Methods: Thirty stable hemodialysis patients with serum albumin levels <3.5 g/dL, normalized protein nitrogen appearance (nPNA) <1.1 g/kg/d, and body mass index (BMI) >20 kg/m 2 were selected: 15 patients were randomized to oral amino acid supplementation (4 g thrice a day) for 3 months and 15 patients comparable for age, gender, and dialysis durations formed the control group. Biochemistry and bioimpedentiometry parameters were measured at baseline and at the end of treatment. Results: No difference was observed between study group and control group at baseline. At the end of the study period, no change occurred in the studied parameters in the control group, whereas increase in serum albumin (3.1 ± 0.3 vs. 3.6 ± 0.2 g/dL, p < 0.001) and in total proteins (5.7 ± 0.4 vs. 6.4 ±0.7 g/dL, p < 0.001) occurred in the study group. Hemoglobin rose from 10.7 ± 0.9 to 11.7 ± 0.8 g/dL (p < 0.05) at the same erythropoiesis-stimulating agent (ESA) dosage. C-Reactive protein (CRP) levels decreased in the study group (8.7 ± 7.3 vs. 3.8 ± 3.1 mg/L, p < 0.01). Increase of body weight and of equilibrated protein catabolic rate (ePCR) was observed in the study group. Conclusions: Oral amino acids supplementation was able to improve albumin and total protein in hypoalbuminemia hemodialysis patients. This effect was associated with reduction of CRP levels that is with lowering of pro-inflammatory status and anemia improvement.

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“…As such, hemodialysis patients are frequently counseled on dietary phosphorus restriction, which may inadvertently lead to a reduction in protein intake [8,12,13]. Second, thrice-weekly dialysis sessions may coincide with core meal times, leading to inadequate food intake on dialysis treatment days [14]. This issue may be compounded by the fact that many outpatient dialysis units in the USA refrain from administering meals and prohibit outside food or beverage consumption during dialysis, given concerns about postprandial hypotension, aspiration, infection risk, staff burden and financial constraints [13,15].…”

Section: Introductionmentioning

confidence: 99%

Effect of high-protein meals during hemodialysis combined with lanthanum carbonate in hypoalbuminemic dialysis patients: findings from the FrEDI randomized controlled trial

Rhee

You

Parsons

et al. 2016

Nephrol. Dial. Transplant.

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Effects of dietary intake, appetite, and eating habits on dialysis and non-dialysis treatment days in hemodialysis patients: cross-sectional results From the HEMO study

Cited by 139 publications

References 15 publications

Is Maximum Conservative Management an Equivalent Treatment Option to Dialysis for Elderly Patients with Significant Comorbid Disease?

Is Maximum Conservative Management an Equivalent Treatment Option to Dialysis for Elderly Patients with Significant Comorbid Disease?

A Novel Amino Acids Oral Supplementation in Hemodialysis Patients: a Pilot Study

Effect of high-protein meals during hemodialysis combined with lanthanum carbonate in hypoalbuminemic dialysis patients: findings from the FrEDI randomized controlled trial

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