Effects of Finasteride (1 mg) on Hair Transplant

Leavitt, Matt; Pérez-Meza, David; Rao, Naveen A.; Barusco, Marco N.; Kaufman, Keith D.; Ziering, Craig

doi:10.1111/j.1524-4725.2005.31202

Cited by 40 publications

(27 citation statements)

References 19 publications

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“…It is a safe and effective treatment for men who cannot accept the hair loss related with AGA. Practically, it has no side effects in men (it causes sexual dysfunction in about 2% of men) [ 85 ].…”

Section: Hair Diseases Of the Pubertymentioning

confidence: 99%

“…The use of this technique allows to obtain an effect that is the most consistent with the patient's expectations, but also with a further prognosis of baldness development. Contradictions to this procedure are compensation of psychological problems, exaggerated expectations of a patient, active skin diseases, a negative ratio of the donor area to the size of baldness and tendency for keloids development [ 85 ].…”

Section: Hair Diseases Of the Pubertymentioning

confidence: 99%

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Dermatological problems of the puberty

Bergler‐Czop

Brzeźińska-Wcisło²

2013

pdia

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Puberty is a period of life between childhood and adulthood. It is characterized by many changes in morphology and appearance of the body (biological maturation), in the psyche – development of personality (psychological maturation), and in the attitude towards one's own and the opposite sex (psychosexual maturation), and in the social role (social maturation). Dermatological problems of adolescence are mainly related to fluctuations in hormone levels, mainly androgens. They include acne, hair problems and excessive sweating. Acne vulgaris is the most frequently diagnosed dermatosis in patients aged between 11 and 30 years. It is believed that it affects about 80% of persons in this age group or even, taking into account lesions of low intensity, 100% of young people. Excessive sweating is a condition characterised by excessive production of sweat, resulting from high activity of sweat glands. The sweat glands are localised in almost all areas of the body surface but on the hands, feet, armpits and around the groin they are found at the highest density. Seborrhoeic dermatitis of the scalp is a chronic, relapsing, inflammatory dermatosis, which currently affects about 5% of the population. It affects mostly young people, particularly men.

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Section: Hair Diseases Of the Pubertymentioning

confidence: 99%

Section: Hair Diseases Of the Pubertymentioning

confidence: 99%

Dermatological problems of the puberty

Bergler‐Czop

Brzeźińska-Wcisło²

2013

pdia

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“…Robust terminal hair follicles and hair follicles in groups have a better HTS survival than weaker hairs and single hair follicular units. Their vigor can be improved slightly with finasteride and minoxidil,[3–5] but it is not likely that the patient will continue indefinitely with medical treatment. Additionally, miniaturizing hair and smaller follicular units usually mean that the donor zone is being affected by AGA and that the transplanted grafts can be expected to considerably weaken with time.…”

Section: Patient Selection: Donor Scalp Issuesmentioning

confidence: 99%

Review of factors affecting the growth and survival of follicular grafts

Parsley

Pérez-Meza²

2010

J Cutan Aesthet Surg

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“…Furthermore, these symptoms are due to the functional loss of follicular stem cell activity (i.e., forming the hair follicles) [ 5 ]. Recently, there have been numerous therapeutic trials of various treatments for hair loss such as oral medications and hair transplantation [ 6 7 ]. However, therapeutic drugs, like finasteride and dutasteride, provide only temporary improvement, and often with reduced effectiveness, which results in immediate hair loss [ 8 9 10 ].…”

Section: Introductionmentioning

confidence: 99%

Human umbilical cord blood mesenchymal stem cells engineered to overexpress growth factors accelerate outcomes in hair growth

Bak

Choi

Kim

et al. 2018

Korean J Physiol Pharmacol

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Human umbilical cord blood mesenchymal stem cells (hUCB-MSCs) are used in tissue repair and regeneration; however, the mechanisms involved are not well understood. We investigated the hair growth-promoting effects of hUCB-MSCs treatment to determine whether hUCB-MSCs enhance the promotion of hair growth. Furthermore, we attempted to identify the factors responsible for hair growth. The effects of hUCB-MSCs on hair growth were investigated in vivo, and hUCB-MSCs advanced anagen onset and hair follicle neogeneration. We found that hUCB-MSCs co-culture increased the viability and up-regulated hair induction-related proteins of human dermal papilla cells (hDPCs) in vitro. A growth factor antibody array revealed that secretory factors from hUCB-MSCs are related to hair growth. Insulin-like growth factor binding protein-1 (IGFBP-1) and vascular endothelial growth factor (VEGF) were increased in co-culture medium. Finally, we found that IGFBP-1, through the co-localization of an IGF-1 and IGFBP-1, had positive effects on cell viability; VEGF secretion; expression of alkaline phosphatase (ALP), CD133, and β-catenin; and formation of hDPCs 3D spheroids. Taken together, these data suggest that hUCB-MSCs promote hair growth via a paracrine mechanism.

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Effects of Finasteride (1 mg) on Hair Transplant

Abstract: For men with androgenetic alopecia, therapy with finasteride 1 mg daily from 4 weeks before until 48 weeks after hair transplant improves scalp hair surrounding the hair transplant and increases hair density.

Cited by 40 publications

References 19 publications

Dermatological problems of the puberty

Dermatological problems of the puberty

Review of factors affecting the growth and survival of follicular grafts

Human umbilical cord blood mesenchymal stem cells engineered to overexpress growth factors accelerate outcomes in hair growth

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