Effects of hypoxic compound exercise to promote HIF‐1α expression on cardiac pumping function, sleep activity behavior, and exercise capacity in Drosophila
Xu Ping,
Qiufang Li,
Meng Ding
et al.
Abstract:Alteration of HIF‐1α expression levels under hypoxic conditions affects the sequence of its downstream target genes thereby producing different effects. In order to investigate whether the effect of hypoxic compound exercise (HE) on HIF‐1α expression alters cardiac pumping function, myocardial structure, and exercise capacity, we developed a suitable model of hypoxic exercise using Drosophila, a model organism, and additionally investigated the effect of hypoxic compound exercise on nocturnal sleep and activit… Show more
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