Effects of immersion in solution of an experimental toothpaste containing S-PRG filler on like-remineralizing ability of etched enamel

Abstract

This study investigated the like-remineralizing ability of experimental toothpaste containing surface reaction-type pre-reacted glassionomer (S-PRG) filler on etched enamel. Human enamel blocks were etched with 35% phosphoric acid and immersed in 5-mL distilled water, fourfold diluted solution of NaF-containing toothpaste, or S-PRG filler-containing experimental toothpaste. Nanoindentation testing was carried out during immersion and the enamel surfaces were observed by scanning electron microscopy. Elemental analysis of the ions in each solution was performed using inductively coupled plasma atomic emission spectroscopy and fluoride electrode. After 1 month of immersion, the hardness and elastic modulus of the specimen immersed in S-PRG filler-containing toothpaste showed significantly greater values than those of the specimen immersed in NaF-containing toothpaste. Considerable amounts of Al, B, Na, Si, Sr, F ions were detected in the solution of S-PRG filler-containing toothpaste. Experimental S-PRG filler-containing toothpaste may enhance the like-remineralizing ability of etched enamel surfaces due to its ion-releasing ability.

Evaluation of selected properties of a new root repair cement containing surface pre-reacted glass ionomer fillers

“…The S-PRG fillers are prepared by the initiation of an acid-base reaction between fluoroboroaluminosilicate glass and aqueous polyacrylic acid. These bioactive S-PRG particles are thought to promote remineralization [13] and induce antibacterial effects [14,15] through the release of multiple ions such as fluoride, strontium, sodium, boron, aluminum and silicon [16,17]. The aim of this study was to evaluate selected antibacterial, physiochemical and bonding properties of a prototype S-PRG filler-based root repair cement in comparison to commercially available materials used as root repair cements, namely MTA and IRM.…”

The effects of single application of pastes containing ion-releasing particles on enamel demineralization

“…The composition except for S-PRG fillers may have little influence to inhibition of the enamel demineralization, because 0 wt% S-PRG fillercontaining paste exhibited a little inhibition of enamel demineralization. S-PRG filler features a glass ionomer phase around the glass core, which slowly releases multiple ions such as Al, B, Na, Si, Sr, and F [13][14][15] . We would speculate that these ions were released from the S-PRG filler-containing paste, inhibiting demineralization of the enamel.…”

“…Recently, nano-hydroxyapatite (nano-HA), which is similar to the apatite crystal of dental enamel, has been proposed for the remineralization of early caries lesions 11,12) . A surface reaction-type pre-reacted glassionomer (S-PRG) filler forms a stable glass-ionomer phase by pre-reacting acid-reactive glass-containing fluoride with polycarboxylic acid in the presence of water [13][14][15] , and it can release Al, B, F, Na, Si, and Sr ions. Supplying Si and Na ions into the surrounding environment leads to a buffering effect 16,17) , further inhibiting demineralization.…”

Antibacterial Effect of Surface Pre-Reacted Glass Ionomer Filler and Eluate–Mini Review

“…Anti-demineralization effects of S-PRG have been observed in denture base resin [13], fissure sealant [14,15], and coating materials [16][17][18]. S-PRG has like-re-mineralizing ability [19][20][21], which is considered to come from its ion-releasing ability. The effects of S-PRG filler and its released ions on hard tissue were extensively investigated, including the anti-demineralization and re-mineralization activity.…”