2023
DOI: 10.1017/s096719942300045x
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Effects of klotho protein or klotho knockdown in porcine oocytes at different stages

Eun Pyo Kim,
Do Yon Kim,
Changhoon Park
et al.

Abstract: Summary Klotho is a protein that plays different functions in female fertility. We have previously reported that klotho protein supplementation during in vitro maturation improves porcine embryo development, while klotho knockout for somatic cell cloning completely blocks full-term pregnancy in vivo. However, the effects of the microinjection of klotho protein or klotho knockdown dual vector in porcine embryos at different time points and the specific molecular mechanisms remain largely unknown. In this stu… Show more

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