Effects of Linear Ablation at the Isthmus Between the Tricuspid Annulus and Inferior Vena Cava for Atrial Flutter on Autonomic Nervous Activity

Cardiac glial cells release neurotrophic S100B upon catheter-based treatment of atrial fibrillation

“…Our study has some limitations: First, we chose patients with an ablation of the CTI as a control group because functional data indicate sparse innervation in that region (21), but detailed neuroanatomical studies are lacking. S100B concentrations increased marginally in this group, supporting that innervation of this area is scarce.…”

“…S3]. Two groups served as controls: patients who underwent an EPS without ablation (n = 19) and patients with typical atrial flutter undergoing sole CTI (n = 21; 1 patient was excluded from all analyses because of a diagnosis of AF), due to the limited autonomic innervation in that region (21). Sample sizes were chosen on the basis of pilot data in the beginning of the study.…”

Noninvasive Assessment of Atrial Substrate Change after Wide Area Circumferential Ablation: A Comparison with Segmental Pulmonary Vein Isolation

“…The WACA procedure included ablation at the cavotricuspid isthmus whereas PVI did not; however ablation at the cavotricuspid isthmus has been shown previously to impact little upon heart rate and HRV measures in a similar time frame and thus is unlikely to be responsible for the differences observed. 29 Direct anatomic correlates with substrate modification from WACA are inferred but cannot be confirmed from this study. Evaluation of patients undergoing lasso guided WACA would make a better measure as discussed above.…”