Effects of luminance combinations on the characteristics of the global flash multifocal electroretinogram (mfERG)

Abstract

The g/f ratio is important in the MOFO mfERG paradigm, since the DC and IC responses change with this ratio. In order to obtain both optimal DC and IC responses, a g/f ratio of 1:1 with focal flash luminance between 100 cd/m(2) and 200 cd/m(2) would be recommended. As the global flash mfERG paradigm is studying the interaction triggered by both flashes, the g/f ratio is a vital parameter for measurement in future studies.

Human Electroretinal Responses to Grating Patterns and Defocus Changes by Global Flash Multifocal Electroretinogram

“…All the grating patterns had the same number of black and white strips within each mfERG hexagonal stimulus and hence the measured luminance of different grating patterns was the same. The ratio of global flash to focal flash was maintained at 1:1 in this study to obtain both optimal DC and IC responses [ 45 ]. The MOFO mfERG results in a direct component (DC) and an induced component (IC) which can be separately measured to assess the outer and inner retinal responses.…”

Early local functional changes in the human diabetic retina: a global flash multifocal electroretinogram study

“…The background luminance of the mfERG display was 100cd/m 2 . At the high contrast level (98%), both the luminance of the bright phase of the multifocal stimulus and the global flashes were set at 200cd/m 2 as suggested by our previous study, in order to obtain optimal DC and IC responses [23]. The dark phase was set at a luminance of 2cd/m 2 .…”

Global flash multifocal electroretinogram: early detection of local functional changes and its correlations with optical coherence tomography and visual field tests in diabetic eyes

“…A VERIS Science 5.1 system (Electro-Diagnostic-Imaging, Redwood City, CA, USA) was used for the MOFO mfERG measurement. The instrumental set-up was similar to that described in our previous studies [32,34,35]. Briefly, the mfERG stimulation was a 103 scaled hexagonal pattern which subtended 47° horizontally and 44° vertically.…”