Effects of Mediterranean diet on sexual function in people with newly diagnosed type 2 diabetes: The MÈDITA trial

Maiorino, Maria Ida; Bellastella, Giuseppe; Caputo, Mariangela; Castaldo, Filomena; Improta, Maria Rosaria; Giugliano, Dario; Esposito, Katherine

doi:10.1016/j.jdiacomp.2016.08.007

Cited by 67 publications

(39 citation statements)

References 32 publications

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“…The Mediterranean diet pattern is associated with small decreases in ED in small, randomized controlled trials among men with diabetes mellitus and metabolic syndrome. 17,21 However, the observed change in sexual function scores in these clinical trials are well below the minimally detectable difference for the EPIC-26 sexual function score (10-12 points) and therefore do not represent clinically meaning changes in sexual function. 35 As suggested by the lower sexual function scores in this study compared to men with prostate cancer on active surveillance in other study populations, 38,39 the effect of Mediterranean diet on sexual functioning may also be diluted among men with prostate cancer and post-surgical or cancer-related sexual dysfunction, which might be less amenable to treatment with dietary changes.…”

Section: Discussionmentioning

confidence: 81%

“…Diet after prostate cancer diagnosis does not appear to be associated with sexual function. The Mediterranean diet pattern is associated with small decreases in ED in small, randomized controlled trials among men with diabetes mellitus and metabolic syndrome . However, the observed change in sexual function scores in these clinical trials are well below the minimally detectable difference for the EPIC‐26 sexual function score (10‐12 points) and therefore do not represent clinically meaning changes in sexual function .…”

Section: Discussionmentioning

confidence: 87%

“…Specific foods (fruits, nuts, vegetables, dairy), nutrients (monounsaturated: saturated fat ratio, flavonoids), and dietary patterns (Mediterranean and energy restricted, including high‐protein and high‐carbohydrate) are associated with erectile function in healthy individuals as well as men with metabolic syndrome . Notably, men with newly diagnosed diabetes mellitus randomized to a Mediterranean diet had a slower decline in sexual function compared to men randomized to a low‐fat diet . Moderate alcohol consumption may also be inversely associated with ED .…”

Section: Introductionmentioning

confidence: 99%

“…12,[16][17][18][19] Notably, men with newly diagnosed diabetes mellitus randomized to a Mediterranean diet had a slower decline in sexual function compared to men randomized to a low-fat diet. 21 Moderate alcohol consumption may also be inversely associated with ED. 22 However, these observed associations may not persist among men with prostate cancer in whom the mechanism of ED could be post-surgical (eg, nerve injury) or cancer-related (eg, radiation, biopsies, cancer anxiety).…”

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confidence: 99%

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Mediterranean diet after prostate cancer diagnosis and urinary and sexual functioning: The health professionals follow‐up study

et al. 2017

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Among men with prostate cancer, diet intake after diagnosis was not significantly associated with urinary or sexual function, although some relationships appeared to differ among men with and without symptoms prior to their prostate cancer diagnosis. Higher vegetable intake and lower polyunsaturated fat intake after prostate cancer diagnosis may be associated with better urinary function. However, this analysis was exploratory, and further research is needed to better delineate these relationships and guide dietary recommendations for men with prostate cancer.

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Section: Discussionmentioning

confidence: 81%

Section: Discussionmentioning

confidence: 87%

Section: Introductionmentioning

confidence: 99%

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confidence: 99%

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Mediterranean diet after prostate cancer diagnosis and urinary and sexual functioning: The health professionals follow‐up study

et al. 2017

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“…In particular, a MedDiet with high use of virgin olive oil, vegetables, fruits, moderate wine intake, whole grains, nuts, fibres and fish was associated with lower risk and severity of ED, mainly in type 2 Diabetes Mellitus, with the highest observance to the MedDiet [5, 6, 7]. …”

Section: Resultsmentioning

confidence: 99%

Mediterranean diet and erectile dysfunction: a current perspective

Francesco

Tenaglia

2017

CEJU

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IntroductionIn this current perspective we analyzed the role of Mediterranean diet (MedDiet) in sexual function and particularly in erectile dysfunction (ED), according to the latest scientific evidence.Material and methodsWe conducted a systematic search of relevant full-length papers identified during the time period from 1 January 2010 to the present.ResultsPublished studies showed that adherence to a MedDiet contributes to preventing ED through an improved lipid and glucose metabolism, increased antioxidant defenses, and increased arginine levels which could raise nitric oxide activity.ConclusionsOur findings suggest that the encouragement of a healthy lifestyle, such as MedDiet promotion, could be an attractive dietary approach to prevent ED and preserve sexual function.

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Association of Diet With Erectile Dysfunction Among Men in the Health Professionals Follow-up Study

et al. 2020

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Key Points Question Is diet quality associated with risk of erectile dysfunction? Findings In this cohort study among 21 469 men in the Health Professionals Follow-up Study, higher diet quality based on adherence to either a Mediterranean or Alternative Healthy Eating Index 2010 diet, which emphasize the consumption of vegetables, fruits, nuts, legumes, and fish or other sources of long-chain (n-3) fats, as well as avoidance of red and processed meats, was found to be associated with a lower risk of developing erectile dysfunction. Meaning These findings suggest that a healthy dietary pattern may play a role in maintaining erectile function in men.

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Effects of Mediterranean diet on sexual function in people with newly diagnosed type 2 diabetes: The MÈDITA trial

Cited by 67 publications

References 32 publications

Mediterranean diet after prostate cancer diagnosis and urinary and sexual functioning: The health professionals follow‐up study

Mediterranean diet after prostate cancer diagnosis and urinary and sexual functioning: The health professionals follow‐up study

Mediterranean diet and erectile dysfunction: a current perspective

Association of Diet With Erectile Dysfunction Among Men in the Health Professionals Follow-up Study

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